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Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

for
Endometrial Cancer, Endometrioid Tumor, Cancer, Tumor,
Location: Providence RI, New York NY, Miami Beach FL,
Sponsor: Aadi Bioscience, Inc.

Sex: All

Age: 18+

Code: NCT05997017

Phase 2, Recruiting

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

for
Clear Cell Renal Cell Carcinoma, Solid Tumors
Location: Boston MA, New York NY, Baltimore MD, Miami FL,
Sponsor: Arcus Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT05536141

Phase 1, Recruiting

000860: A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

for
Brain Tumor, Cancer
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 15 - 70+

Code: NCT05588141

Phase 1, Phase 2, Recruiting

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

for
Advanced or Metastatic Solid Tumors, Breast Cancer,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: 858 Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06395519

Phase 1, Phase 2, Recruiting

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

for
Solid Tumor, Advanced Cancer, Metastatic Cancer, Gastric Cancer,
Location: Boston MA, New York NY, Madison WI, Aurora CO,
Sponsor: I-Mab Biopharma US Limited

Sex: All

Age: 18+

Code: NCT04900818

Phase 1, Recruiting

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Formulating Expert Consensus Guidelines in Cancer Care Using the Delphi Method

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 21+

Code: NCT05054413

Recruiting

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

for
Metastatic Malignant Solid Neoplasm, Metastatic Melanoma,
Location: Duarte CA, Los Angeles CA, Stanford CA
Sponsor: Anusha Kalbasi

Sex: All

Age: 18 - 70+

Code: NCT04119024

Phase 1, Recruiting

Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma

for
Large Cell Lymphoma, Diffuse, Relapsed Cancer,
Location: Charlottesville VA, Detroit MI, Indianapolis IN,
Sponsor: Dipenkumar Modi

Sex: All

Age: 18+

Code: NCT05852717

Phase 2, Recruiting

Adapting for Latinx Populations an Intervention That Involves Discussing and Sharing Patients' Health-Related Values

for
Solid Tumor, Solid Tumor, Adult,
Location: The Bronx NY, New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 21+

Code: NCT04942717

Recruiting

Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06075524

Recruiting

Definitive Radiation for High-Risk Spine Metastases

for
Metastatic Cancer, Metastatic Lung Cancer,
Location: Stony Brook NY
Sponsor: Stony Brook University

Sex: All

Age: 18+

Code: NCT06165419

Phase 2, Recruiting

Study of the Safety and Efficacy of STI-6643 in Subjects With Advanced Solid Tumors

for
Solid Tumor, Relapsed Solid Neoplasm, Refractory Tumor
Location: Fairfax VA, Sioux Falls SD, Dallas TX
Sponsor: Sorrento Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04900519

Phase 1, Recruiting

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for
Colorectal Carcinoma, Endometrial Carcinoma, Melanoma,
Location: Boston MA, New York NY, Philadelphia PA,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 30

Code: NCT04851119

Phase 1, Phase 2, Recruiting

Complications and Clinical Response in Cancer Patients Treated With Anti-VEGF-Related Therapies

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT05108519

Recruiting

Evaluation of the Efficacy and Safety of [18F]-ML-10, as a PET Imaging Radiotracer, in Early Detection of Response of Brain Metastases of Solid Tumors to Radiation Therapy.

for
Brain Metastases, Solid Tumors
Location: Boston MA, New York city NY, Pittsburgh PA
Sponsor: Aposense Ltd.

Sex: All

Age: 18+

Code: NCT00805636

Phase 2, Recruiting

Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors

for
Recurrent or Refractory Solid Tumors, Ewing Sarcoma,
Location: Cincinnati OH, Milwaukee WI, Dallas TX,
Sponsor: South Plains Oncology Consortium

Sex: All

Age: 1 - 20

Code: NCT02013336

Phase 1, Recruiting

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

for
Advanced Solid Tumors, Metastatic Pancreatic Cancer,
Location: Bethesda MD, Fairway KS
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12 - 70+

Code: NCT04222413

Phase 1, Recruiting

Identify Barriers to Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Newly Diagnosed and Relapsed Acute Leukemia

for
Acute Leukemia, Newly Diagnosed, Relapsed
Location: Hartford CT, New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT02677064

Recruiting

Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology

for
Muscle-Invasive Bladder Carcinoma, Tumor
Location: Los Angeles CA
Sponsor: Leslie Ballas

Sex: All

Age: 18+

Code: NCT06417190

Phase 2, Recruiting

Zanubrutinib With Pemetrexed to Treat Relapsed/Refractory Primary and Secondary Central Nervous System (CNS) Lymphomas

for
Primary Central Nervous System Lymphoma,
Location: Miami FL
Sponsor: Baptist Health South Florida

Sex: All

Age: 18+

Code: NCT05681195

Phase 2, Recruiting