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A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.

for
Triple Negative Breast Cancer, Diffuse Large B Cell Lymphoma,
Location: Fairfax VA, Pittsburgh PA, Canton OH, Columbus OH,
Sponsor: OncoNano Medicine, Inc.

Sex: All

Age: 18+

Code: NCT06022029

Phase 1, Recruiting

A Prospective, Single Blinded Study for Predicting Colon Polyp Histology With Narrow Band Imaging

for
Colonoscopy, Adenomatous Polyp, Neoplastic
Location: Kansas City MO
Sponsor: Midwest Biomedical Research Foundation

Sex: All

Age: 18+

Code: NCT00613262

Recruiting

Phase II Study of Pembrolizumab in Combination With Lenvatinib in Patients With TNBC, NSCLC, and Other Tumor Types and Brain Metastases

for
Brain Metastases, Tumor
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05064280

Phase 2, Recruiting

A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body

for
Melanoma, Clear-Cell Renal-Cell Carcinoma (ccRCC),
Location: North Haven CT, Lake Success NY, Chapel Hill NC,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06413680

Phase 1, Phase 2, Recruiting

Dose-escalation Study of Oral CX-4945

for
Advanced Solid Tumors, Breast Cancer,
Location: Houston TX, Fort Collins CO, Loveland CO, Scottsdale AZ
Sponsor: Cylene Pharmaceuticals

Sex: All

Age: 18+

Code: NCT00891280

Phase 1, Recruiting

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Targeted Therapy to Increase RAI Uptake in Metastatic DTC

for
Papillary Thyroid Cancer, Pediatric Cancer,
Location: Boston MA, Philadelphia PA, Atlanta GA, Memphis TN,
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 0+

Code: NCT05024929

Recruiting

Fatty Acid Synthase Inhibition in Castration Refractory Prostate Cancer

for
Prostate Cancer, Refractory Cancer,
Location: Winston-Salem NC, Salisbury NC
Sponsor: Wake Forest University Health Sciences

Sex: Male

Age: 18+

Code: NCT04337580

Phase 2, Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in Patients With Advanced Solid Tumor

for
Neoplasms, Tenosynovial Giant Cell Tumor
Location: Beverly Hills CA
Sponsor: Abbisko Therapeutics Co, Ltd

Sex: All

Age: 18+

Code: NCT04192344

Phase 1, Recruiting

Cancer Genetic Testing in Ethnic Populations

for
Breast Carcinoma, Carcinoma of Unknown Primary,
Location: Jacksonville FL, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04475640

Recruiting

A Beta-only IL-2 ImmunoTherapY Study

for
Advanced Solid Tumor, Unresectable Solid Tumor,
Location: Boca Raton FL, Toronto, Detroit MI, Atlanta GA,
Sponsor: Medicenna Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05086692

Phase 1, Phase 2, Recruiting

INTERogating Cancer for Etiology, Prevention and Therapy Navigation

for
Cancer, Cancer Gene Mutation, PAN Gene Mutation,
Location: Jacksonville FL, La Crosse WI, Eau Claire WI,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06008392

Recruiting

Lurbinectedin in FET-Fused Tumors

for
Ewing Sarcoma, Desmoplastic Small Round Cell Tumor,
Location: Boston MA, New York NY, Philadelphia PA, Ann Arbor MI,
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 10+

Code: NCT05918640

Phase 1, Phase 2, Recruiting

Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Boston MA, Pittsburgh PA, Houston TX, Newport Beach CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12+

Code: NCT05372640

Phase 1, Recruiting

Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies

for
Solid Tumor, Adult, Triple Negative Breast Cancer,
Location: Scottsdale AZ, La Jolla CA, Stanford CA
Sponsor: BioEclipse Therapeutics

Sex: All

Age: 18+

Code: NCT04282044

Phase 1, Recruiting

Synapse 3D With Intravascular Indocyanine Green

for
Non-small Cell Lung Cancer, Primary Neoplasm
Location: Hamilton
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 18+

Code: NCT03953144

Phase 1, Phase 2, Recruiting

Trial of DFP-14927 in Advanced Solid Tumors

for
Solid Tumor, Cancer
Location: Houston TX, Los Angeles CA
Sponsor: Delta-Fly Pharma, Inc.

Sex: All

Age: 18+

Code: NCT03943004

Phase 1, Recruiting

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

for
Rectal Adenocarcinoma, Clinical Stage: Stage II (T3-4, N-),
Location: Hartford CT, Commack NY, Uniondale NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT04165772

Phase 2, Recruiting

Registry of Older Patients With Cancer

for
Chronic Myeloproliferative Disorders,
Location: Morehead City NC, New Bern NC, Greenville NC,
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 65+

Code: NCT01137825

Recruiting

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

for
Solid Tumor, Adult, Refractory Cancer,
Location: Boston MA, New Haven CT, New York NY, Fairfax VA,
Sponsor: GV20 Therapeutics

Sex: All

Age: 18+

Code: NCT05669430

Phase 1, Phase 2, Recruiting

Stereotactic Ablative Radiotherapy for Oligo-Progressive Disease REfractory to Systemic Therapy in Metastatic Cancer

for
Metastatic Cancer, Oligoprogressive
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18+

Code: NCT04989725

Phase 2, Recruiting