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FORTRAS: A Study of MSK-TCR5 in People With Solid Tumor Cancers

for
Solid Tumor, Solid Carcinoma, Advanced Solid Tumor,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07638371

Phase 1, Recruiting

Dose-Escalation and Dose-Expansion Study of BSI-082 Monotherapy and Combined Therapy in Patients With Advanced or Metastatic Solid Tumors

for
Solid Tumor, Advanced Solid Tumor, Metastatic Solid Tumor
Location: San Antonio TX
Sponsor: Lei Zheng

Sex: All

Age: 18+

Code: NCT07086768

Phase 1, Recruiting

(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors

for
Advanced Gastrointestinal Stromal Tumors, Metastatic Cancer
Location: New York NY, Washington D.C. DC, Miami FL, Orlando FL,
Sponsor: Cogent Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT05208047

Phase 3, Recruiting

Ph. I/II Sodium Thiosulfate for OtoProtection During Cisplatin (STOP-CIS)

for
Solid Tumor Malignancies, Testicular Cancer,
Location: Tucson AZ
Sponsor: University of Arizona

Sex: All

Age: 18+

Code: NCT07407582

Phase 1, Phase 2, Recruiting

A Study of Mutant Selective-Inhibitor (CGT6297), in Patients With Advanced Solid Tumors

for
PIK3CA Mutations, Advanced Solid Tumors, Adult,
Location: Boston MA, East Brunswick NJ, Fairfax VA, Tampa FL,
Sponsor: Cogent Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07383506

Phase 1, Recruiting

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A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

for
Advanced Solid Tumor, Non-Small Cell Lung Cancer,
Location: Fairfax VA, Tampa FL, Sarasota FL
Sponsor: Blueprint Medicines Corporation

Sex: All

Age: 18+

Code: NCT07629960

Phase 1, Phase 2, Recruiting

A First-in-human Study of RLY-8161 in Advanced NRAS-Mutant Solid Tumors

for
Advanced NRAS-Mutant Melanoma,
Location: Boston MA, New York NY, Fairfax VA, Grand Rapids MI,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07584226

Phase 1, Recruiting

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

for
Recurrent Glioblastoma,
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT07416188

Phase 1, Phase 2, Recruiting

Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy

for
Locally Advanced Cancer, Metastatic Cancer, HER2,
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT06828588

Early Phase 1, Recruiting

Optimizing Health Related Quality of Life Measurement in Adolescent and Young Adult Oncology

for
Malignant Solid Neoplasm, Hematopoietic Neoplasms,
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 15+

Code: NCT06897137

Recruiting

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

for
Advanced Biliary Tract Carcinoma,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT07405086

Phase 4, Recruiting

Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue Sarcoma

for
Phase 2, Zanzalintinib, Pembrolizumab, Advanced/Metastatic,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07283731

Phase 2, Recruiting

A Phase 1 Dose Escalation and Dose Expansion Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

for
KRAS-mutant Non-small Cell Lung Cancer (NSCLC),
Location: Boston MA, Philadelphia PA, Fairfax VA, Tampa FL,
Sponsor: Kestrel Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07458347

Phase 1, Recruiting

Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and Interception (SHERLOCK)

for
Breast Cancer, Lung Cancer, Melanoma, Gynecologic Cancer,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT07524114

Recruiting

Telephone-Based Coaching Sessions (TAC) to Improve Advance Care Planning Participation in Advanced Cancer Patients and Their Support Person

for
Advanced Malignant Solid Neoplasm,
Location: Mount Vernon WA, Everett WA, Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT07141407

Recruiting

NCI Childhood Cancer Data Initiative (CCDI) Led Pediatric, Adolescent, and Young Adult Rare Cancer Registry for Very Rare Solid Tumors

for
Very Rare Tumors, Very Rare Cancers, Other Solid Tumors,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 70+

Code: NCT07489378

Recruiting

Patient Interest in an Integrative Oncology Program at USC Norris Cancer Center: A Single-Institution Needs Assessment

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT07306338

Recruiting

A Study of BI 3810944 in Patients With Advanced Cancer

for
Solid Tumours, Melanoma
Location: Louisville KY, Nashville TN
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT07224425

Phase 1, Recruiting

Distance-Based Exercise to Preserve Function and Prevent Disability

for
Localized Malignant Solid Neoplasm, Anal Cancer,
Location: Boston MA, Indiana PA, Kernersville NC,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07059884

Recruiting

Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLC

for
Metastatic Non-Squamous Non-Small Cell Lung Cancer,
Location: Mineola NY, New York NY, Durham NC, Birmingham AL,
Sponsor: CatalYm GmbH

Sex: All

Age: 18+

Code: NCT07246863

Phase 2, Recruiting