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Study of Inherited Neurological Disorders

for
Motor Neuron Disease, Muscular Disease, Muscular Dystrophy,
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 2 - 70+

Code: NCT00004568

Recruiting

Surgery as a Treatment for Medically Intractable Epilepsy

for
Epilepsy, Epilepsy, Temporal Lobe, Partial Epilepsy
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 8 - 70+

Code: NCT01273129

Recruiting

Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database

for
Epilepsy
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 8 - 70+

Code: NCT02107989

Recruiting

Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery

for
Pituitary Neoplasm
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT03678389

Recruiting

Phenotype/Genotype Correlations in Movement Disorders

for
Movement Disorder
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 2 - 70+

Code: NCT00018889

Recruiting

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Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA)

for
Spinal and Bulbar Muscular Atrophy, Kennedys Disease,
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: Male

Age: 18 - 70+

Code: NCT04944940

Recruiting

Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

for
Frontotemporal Dementia, Amyotrophic Lateral Sclerosis,
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT03225144

Recruiting

Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy

for
Progressive Multifocal Leukoencephalopathy, Multiple Sclerosis,
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT05849467

Phase1, Recruiting

Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and Effort

for
Fatigue Syndrome, Chronic
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 50

Code: NCT06472622

Early_phase1, Recruiting

Tumor Related Epilepsy

for
Epilepsy, Cancer, Brain Neoplasm
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 8 - 70+

Code: NCT02639325

Recruiting

Magnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS)

for
Multiple Sclerosis
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT00001248

Recruiting

Natural History Protocol for Movement Disorders

for
Movement Disorder, Tremor, Parkinson's Disease
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 2 - 70+

Code: NCT05413291

Recruiting

Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health

for
Post-Coronavirus Disease 19
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT04573062

Recruiting

Investigational Use of Neuromuscular Ultrasound

for
Muscular Dystrophy, Peripheral Neuropathy,
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT05237973

Recruiting

Deep Brain Stimulation Surgery for Movement Disorders

for
Parkinson's Disease, Essential Tremor, Dystonia
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT01581580

Recruiting

Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy

for
Epilepsy
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 60

Code: NCT02531880

Phase1, Recruiting

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

for
Recurrent Glioblastoma,
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT07416188

Phase1, Phase2, Recruiting

Steady Stride Fall Prevention Protocol vs Standard of Care

for
Fall Prevention, Falls
Location: Baltimore MD
Sponsor: Steady Strides: Fall Prevention and Stroke Rehabilitation Medical Institute

Sex: All

Age: 65+

Code: NCT07092176

Recruiting

DDAVP for Pituitary Adenoma

for
Cushing's Disease, Pituitary Adenoma
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 8 - 70+

Code: NCT04569591

Recruiting

Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot Study

for
Progressive Multifocal Leukoencephalopathy
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT07511049

Phase2, Recruiting