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COvid-19 Vaccine Booster in Immunocompromised Rheumatic Diseases

for
Rheumatoid Arthritis, Autoimmune Rheumatologic Disease,
Location: Quebec, Montreal
Sponsor: Paul R Fortin

Sex: All

Age: 18+

Code: NCT05236491

Phase2, Phase3, Recruiting

A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants

for
Systemic Lupus Erythematosus (SLE) or Cutaneous Lupus Erythematosus,
Location: Orlando FL, Clearwater FL, Irving TX, San Antonio TX,
Sponsor: DualityBio Inc.

Sex: All

Age: 18 - 70

Code: NCT06625671

Phase1, Phase2, Recruiting

US Zamto-cel Autoimmune Diseases

for
Lupus Nephritis, Systemic Lupus Erythematosus,
Location: Milwaukee WI
Sponsor: Miltenyi Biomedicine GmbH

Sex: All

Age: 18+

Code: NCT06708845

Phase1, Recruiting

A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus

for
Systemic Lupus Erythematosus
Location: Miami FL, New Albany IN, Willowbrook IL, Memphis TN,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70

Code: NCT07430306

Phase3, Recruiting

Alnuctamab for Refractory SLE (LATTE Study)

for
Systemic Lupus Erythematosus
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 18 - 60

Code: NCT07219563

Phase1, Recruiting

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Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants

for
Rheumatoid Arthritis, Systemic Lupus Erythematosus
Location: Mesquite TX, Allen TX, Fullerton CA
Sponsor: AstraZeneca

Sex: All

Age: 18 - 65

Code: NCT07201558

Phase1, Recruiting

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus

for
Cutaneous Lupus Erythematosus (CLE),
Location: Fairport NY, DeBary FL, Tampa FL, Clearwater FL,
Sponsor: Ventus Therapeutics U.S., Inc.

Sex: All

Age: 18 - 70+

Code: NCT07260877

Phase2, Recruiting

A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants

for
Systemic Lupus Erythematosus (SLE)
Location: Calgary, West Long Branch NJ, Brooklyn NY, Ottawa,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 16+

Code: NCT07175285

Recruiting

Safety and Efficacy of ONT01 in Lupus

for
Lupus Nephritis (LN), Lupus Nephritis - WHO Class III,
Location: New York NY
Sponsor: Hospital for Special Surgery, New York

Sex: All

Age: 18+

Code: NCT07107659

Early_phase1, Recruiting

A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)

for
Systemic Lupus Erythematosus
Location: Aventura FL, Duncansville PA, Tampa FL,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18 - 70+

Code: NCT07409181

Phase2, Recruiting

CorEvitas Systemic Lupus Erythematosus (SLE) Drug Safety and Effectiveness Registry

for
Systemic Lupus Erythematosus
Location: Waltham MA
Sponsor: CorEvitas

Sex: All

Age: 18+

Code: NCT06804057

Recruiting

Anifrolumab Pregnancy Study

for
Systemic Lupus Erythematosus
Location: Cary NC
Sponsor: AstraZeneca

Sex: Female

Age: 18 - 70+

Code: NCT07049653

Recruiting

A Study to Continue the Administration of Deucravacitinib in Participants With Systemic Lupus Erythematosus (SLE) or Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE) Who Have Completed Study IM011074 or Study IM011132

for
Systemic Lupus Erythematosus (SLE),
Location: New York NY, Oklahoma City OK
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 70+

Code: NCT06875960

Recruiting

A Phase 1b Study of Budoprutug in Systemic Lupus Erythematosus (SLE)

for
Systemic Lupus Erythematosus
Location: San Antonio TX, Allen TX
Sponsor: Climb Bio, Inc.

Sex: All

Age: 18 - 65

Code: NCT07011043

Phase1, Recruiting

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

for
Systemic Lupus Erythematosus (With and Without Nephritis),
Location: New York NY, East Brunswick NJ, Montreal, Baltimore MD,
Sponsor: Allogene Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07085104

Phase1, Recruiting

A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

for
Systemic Lupus Erythematosus,
Location: Boston MA, Great Neck NY, New York NY, Rochester NY,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT06570798

Phase2, Recruiting

BAFF CAR-T Cells (LMY-920) for Systemic Lupus Erythematosus

for
Systemic Lupus Erythematosus
Location: Columbus OH
Sponsor: Luminary Therapeutics

Sex: All

Age: 18 - 65

Code: NCT06340750

Phase1, Recruiting

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

for
Systemic Lupus Erythematosus
Location: New Hyde Park NY, Valhalla NY, The Bronx NY,
Sponsor: AstraZeneca

Sex: All

Age: 5 - 17

Code: NCT05835310

Phase3, Recruiting

Nature of Anifrolumab Impact on Vaccine-Emergent Immunity in SLE

for
Systemic Lupus Erythematosus (SLE)
Location: Oklahoma City OK
Sponsor: Oklahoma Medical Research Foundation

Sex: All

Age: 18 - 70

Code: NCT04726553

Early_phase1, Recruiting

Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires

for
Systemic Lupus Erythematosus (Sle),
Location: Bethesda MD
Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Sex: Female

Age: 18 - 70+

Code: NCT05567198

Recruiting