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Phase III Extension Study of Efficacy and Safety of Ianalumab With or Without Study Treatment Withdrawal in Participants With Lupus Nephritis (SIRIUS-LN Extension)

for
Lupus Nephritis
Location: Orchard Park NY
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT06711887

Phase3, Recruiting

Wellness & Workforce Solution for Lupus/Lupus Nephritis

for
Lupus Nephritis
Location: Atlanta GA
Sponsor: Morehouse School of Medicine

Sex: Female

Age: 18+

Code: NCT06217107

Recruiting

A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus

for
Lupus Erythematosus, Systemic
Location: Newark NJ, Voorhees Township NJ, Philadelphia PA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18 - 70+

Code: NCT07438496

Phase3, Recruiting

A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment

for
Nephritis, Lupus, Lupus Erythematosus, Systemic
Location: Miami FL, Miami Lakes FL, Doral FL, Kissimmee FL,
Sponsor: Viatris Innovation GmbH

Sex: All

Age: 18 - 70+

Code: NCT07201129

Phase3, Recruiting

A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101

for
Refractory Lupus Nephritis, Myasthaenia Gravis,
Location: Denver CO
Sponsor: Kyverna Therapeutics

Sex: All

Age: 18+

Code: NCT07403188

Recruiting

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The RheumSafer Study: Improving Medication Appropriateness in People With Rheumatic Conditions

for
Rheumatic Diseases, Inflammatory Arthritis,
Location: Montreal
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All

Age: 60+

Code: NCT07278609

Recruiting

Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)

for
Lupus Nephritis
Location: New York NY, Syracuse NY, San Antonio TX
Sponsor: Autolus Limited

Sex: All

Age: 12 - 65

Code: NCT07053800

Phase2, Recruiting

PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis

for
Lupus Nephritis
Location: West Long Branch NJ, Willow Grove PA, Rockville MD,
Sponsor: Aurinia Pharmaceuticals Inc.

Sex: All

Age: 18 - 70+

Code: NCT07611214

Recruiting

Dapagliflozin in Active Lupus Nephritis

for
Lupus Nephritis (LN)
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18 - 70

Code: NCT07323524

Recruiting

Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis

for
Lupus Nephritis (LN)
Location: Rochester MN, Houston TX
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18 - 60

Code: NCT06975787

Phase1, Recruiting

A Prospective Real World Evidence Study (PROWES) for Concordance Rate of Blood-based 3D Genome Conformation Mapping (Episwitch CiRT®) to Identify Likelihood of Response and Actual Response Rates to PD-(L)-1 Checkpoint Inhibitors Across Multiple Oncological Indications.

for
Cancer, Immunotherapy, PD-1, PD-L1, Immune Checkpoint Therapy
Location: Norwich CT, Rock Hill SC, Dublin GA
Sponsor: Oxford Biodynamics Inc.

Sex: All

Age: 18+

Code: NCT06635954

Recruiting

Correlation Vitamin D Level to Endocrine Autoimmune Toxicity Due to Immune Checkpoint Inhibitors

for
Thyroid, PD-1, Cancer
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 18+

Code: NCT04615988

Recruiting

Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor

for
SIOD, Cystinosis, FSGS, SLE Nephritis, CKD Stage 4
Location: Palo Alto CA
Sponsor: Alice Bertaina

Sex: All

Age: 1 - 30

Code: NCT05508009

Phase1, Phase2, Recruiting

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

for
Lupus Erythematosus, Systemic
Location: Boston MA, New York NY, Syracuse NY, Chapel Hill NC,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70

Code: NCT06897930

Phase1, Phase2, Recruiting

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus

for
SLE, SLE (Systemic Lupus)
Location: New York NY, Rochester NY, Orlando FL, Memphis TN,
Sponsor: Cullinan Therapeutics Inc.

Sex: All

Age: 18 - 70

Code: NCT06613360

Phase1, Recruiting

Relationship Between Data Obtained With the LuGENE® Multiparameter Transcriptomics Blood Test and Clinical and Standard Laboratory Features of Patients With SLE (ReLATE)

for
Lupus Erythematosus, Systemic
Location: Manhasset NY, Charlotte NC, Los Angeles CA
Sponsor: Ampel BioSolutions, LLC

Sex: All

Age: 18+

Code: NCT05845593

Recruiting

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)

for
Systematic Lupus Erythematosus, Cutaneous Lupus Erythematosus
Location: Smithfield NC, Hollywood FL, Pembroke Pines FL,
Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07355218

Phase3, Recruiting
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A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE), Sjogren's Disease (SjD) and Rheumatoid Arthritis (RA)

for
Dry Eye Syndrome, Systemic Lupus Erythematosus
Location: Margate FL, Tampa FL, Orland Park IL, Memphis TN,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT06977724

Phase1, Recruiting

Feasibility of an Immersive Virtual Reality Based Biofeedback Intervention for Outpatients in Rheumatology

for
Rheumatoid Arthritis, Systemic Lupus Erythematosus,
Location: Beverly Hills CA
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18+

Code: NCT03459274

Recruiting

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease

for
Systemic Lupus Erythematosus (SLE),
Location: Tamarac FL, Cooper City FL, Miami FL, Tampa FL, Troy MI,
Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07332481

Phase3, Recruiting