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Active & Responsive

Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatment

for
Overweight and Obesity
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18+

Code: NCT06069622

Recruiting
Active & Responsive

Collaborative Care for Treatment of Depression and Anxiety

for
Depression, Anxiety
Location: Aurora CO
Sponsor: Kaiser Permanente

Sex: All

Age: 18+

Code: NCT06556589

Recruiting
Active & Responsive

OSTEOAMP Lumbar Fusion Intra-Patient Controlled Study

for
Lumbar Spine Disease, Lumbar Spondylolisthesis,
Location: Boston MA, New Haven CT, Richmond VA, Morgantown WV,
Sponsor: Bioventus LLC

Sex: All

Age: 21 - 70+

Code: NCT05405374

Recruiting
Active & Responsive

Sex Differences in the Response to Abstinence From Alcohol.

for
Alcohol Use Disorder
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 21 - 35

Code: NCT03827460

Phase 1, Recruiting
Active & Responsive

SMARTer Weight Loss Management

for
Obesity
Location: Tallahassee FL
Sponsor: Florida State University

Sex: All

Age: 18+

Code: NCT05861973

Recruiting

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Active & Responsive

SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

for
Chronic Kidney Diseases, End Stage Renal Disease,
Location: Boston MA, Lake Success NY, Raleigh NC, Florence SC,
Sponsor: VenoStent

Sex: All

Age: 18+

Code: NCT06001827

Recruiting
Active & Responsive

The Metabolic Effects of Intermittent Fasting

for
Normal and Overweight Individuals at High-risk of Diabetes
Location: Pittsburgh PA
Sponsor: University of Pittsburgh

Sex: All

Age: 21 - 45

Code: NCT05722873

Recruiting
Active & Responsive

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain

for
Osteoarthritis, Knee, Diabetic Neuropathic Pain,
Location: New Bedford MA, Waltham MA, Hamden CT, Rochester NY,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT05986292

Phase 2, Recruiting
Active & Responsive

ARISe at UMass Chan

for
Vaccination, Vaccination Promotion
Location: Worcester MA
Sponsor: University of Massachusetts, Worcester

Sex: All

Age: 18+

Code: NCT07236034

Recruiting
Active & Responsive

Prospective Multi-Center Trial for FemBloc Permanent Birth Control

for
Contraception
Location: New York NY, Brooklyn NY, Macon GA, Cincinnati OH,
Sponsor: Femasys Inc.

Sex: Female

Age: 21 - 50

Code: NCT05977751

Recruiting
Active & Responsive

Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

for
Knee Cartilage Defects
Location: Flushing NY, New York NY, Westwood NJ, Morehead City NC,
Sponsor: Medipost, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07339111

Phase 3, Recruiting
Active & Responsive

A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder

for
Major Depressive Disorder
Location: New York NY, Hollywood FL, Miami FL, Orlando FL,
Sponsor: AbbVie

Sex: All

Age: 18 - 65

Code: NCT07276997

Phase 2, Recruiting
Active & Responsive

Blossom® Smart Expander Device for Tissue Expander/Implant-Based Breast Reconstruction

for
Tissue Expansion, Implant Based Breast Reconstruction
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18 - 65

Code: NCT05975372

Recruiting
Active & Responsive

Chronic Infections and Inflammation in ME/CFS: An Observational Study

for
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT07227441

Recruiting
Active & Responsive

Communicating About Nicotine Reduction in Cigarettes

for
Tobacco Products, Smoking Behavior, Cigarette Use
Location: Atlanta GA
Sponsor: Georgia State University

Sex: All

Age: 21+

Code: NCT06787937

Recruiting
Active & Responsive

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

for
Obesity, Heart Failure
Location: Moncton, Quebec, Sherbrooke, Chicoutimi, Brooklyn NY,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 18+

Code: NCT07567001

Phase 3, Recruiting
Active & Responsive

A Study to Learn About the Safety of BIIB142 and How it is Processed in the Body of Healthy Adult Participants Aged 18 to 55 Years Old

for
Healthy Volunteer
Location: Las Vegas NV
Sponsor: Biogen

Sex: All

Age: 18 - 55

Code: NCT07133828

Phase 1, Recruiting
Active & Responsive

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

for
Parkinson Disease
Location: Boston MA, New Haven CT, New York NY, Montreal,
Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All

Age: 30+

Code: NCT04477785

Recruiting
Active & Responsive

A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)

for
Idiopathic Hypersomnia
Location: East Providence RI, Boston MA, New Hyde Park NY,
Sponsor: Harmony Biosciences Management, Inc.

Sex: All

Age: 18+

Code: NCT07500090

Phase 3, Recruiting
Active & Responsive

Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention

for
Inflammatory Bowel Disease (IBD), Crohn's Disease,
Location: New York NY, Chapel Hill NC
Sponsor: Mercy Medical Center

Sex: All

Age: 18+

Code: NCT06750731

Recruiting