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Enfortumab Vedotin, Pembrolizumab and Quemliclustat for the Treatment of Unresectable Locally Advanced and Metastatic Urothelial Cancer

for
Locally Advanced Bladder Urothelial Carcinoma,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT07667335

Phase1, Phase2, Recruiting
New

Pilot Study: Feasibility and Usability of a Head-Mounted Spatial Computing Device for Intraoperative Visualization During Intraocular Surgery

for
Cataract Surgery
Location: Brentwood NY
Sponsor: Eric Rosenberg

Sex: All

Age: 18 - 70+

Code: NCT07825337

Recruiting
Active & ResponsiveNew

Phase 1 Trial to Study JANX013 and JANX007 Combination in mCRPC

for
Prostate Cancer, Castration-Resistant Prostate Cancer (CRPC),
Location: Nashville TN
Sponsor: Janux Therapeutics

Sex: Male

Age: 18+

Code: NCT07813637

Phase1, Recruiting
New

Reaching Calm: A Digital Intervention to Prevent Perinatal Anxiety Disorders

for
Perinatal Anxiety, Anxiety Sensitivity, Perinatal Depression
Location: Leominster MA
Sponsor: University of Massachusetts, Worcester

Sex: Female

Age: 18+

Code: NCT07458698

Recruiting
New

Buspirone for Anxiety in Autistic Youth

for
Anxiety, Autism Spectrum Disorder
Location: Lexington MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 7 - 17

Code: NCT07439042

Recruiting

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The Gender Inclusive Sexuality Talks Program

for
HIV/STI Incidence, Communication About Health Information
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 12 - 70+

Code: NCT07825571

Recruiting
New

Vagina-View Safety and Imaging Feasibility

for
Vaginal Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: Female

Age: 18+

Code: NCT07818850

Recruiting
New

A Study to Find an Efficacious and Safe Dose of CHF10067 (Zampilimab) in Participants With Idiopathic Pulmonary Fibrosis

for
Idiopathic Pulmonary Fibrosis
Location: Hannibal MO, Denison TX
Sponsor: Chiesi Farmaceutici S.p.A.

Sex: All

Age: 40+

Code: NCT07516951

Phase2, Recruiting
New

Clinical Outcomes of 3D Printed and Milled Complete Dentures

for
Edentulous Mouth, Edentulous Jaw
Location: Chapel Hill NC
Sponsor: Dentsply Sirona Implants and Consumables

Sex: All

Age: 18+

Code: NCT07586774

Recruiting
New

Weight-Bearing CT Periprosthetic Distal Knee Fractures

for
Periprosthetic Fracture Around Prosthetic Joint Implant Knee
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 50 - 70+

Code: NCT06525610

Recruiting
Active & ResponsiveNew

Safety and Effectiveness of Sebetralstat (KVD900) for Short-Term Prophylaxis Before Procedures in People With Hereditary Angioedema (KONTROL)

for
Hereditary Angioedema
Location: Colorado Springs CO
Sponsor: KalVista Pharmaceuticals, Ltd.

Sex: All

Age: 12+

Code: NCT07654829

Recruiting
New

Thermoregulatory Physiology of Menopausal Hot Flashes

for
Menopause Hot Flashes
Location: Menlo Park CA
Sponsor: SRI International

Sex: Female

Age: 40 - 65

Code: NCT07824648

Recruiting
New

Mycophenolate Mofetil w/ Prednisone for Immune Related Hepatitis From Checkpoint Inhibitor Therapy

for
Immune-mediated Hepatitis, Immune-related Adverse Event
Location: Philadelphia PA
Sponsor: Fox Chase Cancer Center

Sex: All

Age: 18+

Code: NCT07663422

Phase2, Recruiting
New

Exercise Training Decreases Alcohol Consumption and Tissue Injury by an FGF21-dependent Mechanism

for
Alcohol Use Disorder (AUD), Alcohol Related Liver Disease
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18+

Code: NCT07824089

Recruiting
Active & ResponsiveNew

A Phase IIa Study of ICG318 CAR-T in Refractory Systemic Lupus Erythematosus With or Without Lupus Nephritis

for
Systemic Lupus Erythematosus (SLE), Lupus Nephritis (LN)
Location: New Hyde Park NY
Sponsor: iCell Gene Therapeutics

Sex: All

Age: 16 - 70

Code: NCT07328581

Phase2, Recruiting
Active & ResponsiveNew

Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety: R33 Phase

for
Anxiety Disorders
Location: Denver CO
Sponsor: University of Denver

Sex: All

Age: 10 - 17

Code: NCT07818876

Recruiting
New

Hinge vs CCK Implants

for
Revision Arthroplasty, Knee
Location: Washington D.C. DC, Olney MD
Sponsor: Medstar Health Research Institute

Sex: All

Age: 18 - 70+

Code: NCT07818343

Recruiting
New

Treating Young Children With Attention Deficit Hyperactivity Disorder

for
Attention-Deficit/Hyperactivity Disorder (ADHD)
Location: Boston MA, Philadelphia PA, Cincinnati OH,
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 3 - 5

Code: NCT07300956

Recruiting
Active & ResponsiveNew

Phage-based Control and Limitation of Pathobionts for Microbiome Equilibrium and Resilience

for
Gastrointestinal Symptoms, Skin Quality
Location: Fort Collins CO
Sponsor: Colorado State University

Sex: All

Age: 18 - 70+

Code: NCT07816809

Recruiting
Active & ResponsiveNew

Study to Assess KN3835 in the Treatment of Flexible/Semi-Flexible Hammertoe (HMT)

for
Flexible Hammertoe, Semi-flexible Hammertoe
Location: Sweetwater FL, Pinellas Park FL, Bedford TX, McAllen TX,
Sponsor: Endo USA Inc., a Keenova Therapeutics Company

Sex: All

Age: 18 - 70+

Code: NCT07759362

Phase3, Recruiting