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iDose TR Administration in an Office-Based Surgery Setting

for
Open Angle Glaucoma (OAG), Ocular Hypertension (OHT)
Location: Austin TX
Sponsor: Glaukos Corporation

Sex: All

Age: 18+

Code: NCT07816692

Recruiting
Active & ResponsiveNew

Outcomes of Neurosurgical Tone Management

for
Spastic/Dystonic Quadriplegia, Cerebral Palsy (CP)
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 6 - 25

Code: NCT07817745

Recruiting
New

BOND: Direct Breastfeeding to Enhance Maternal and Infant Health in Congenital Heart Disease

for
Congenital Heart Disease (CHD)
Location: Charleston SC, Atlanta GA, Ann Arbor MI, Cincinnati OH,
Sponsor: Carelon Research

Sex: All

Age: 18+

Code: NCT07582848

Recruiting
New

Vorasidenib Maintenance for IDH Mutant Astrocytoma

for
IDH-mutant Grade 2 or 3 Astrocytoma
Location: Toronto, Winnipeg
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All

Age: 18+

Code: NCT06809322

Phase3, Recruiting
New

Virtual Reality for Pain and Well-Being in Older Adults

for
Chronic Pain, Kinesiophobia (Fear of Movement)
Location: Sainte-Marie, Quebec
Sponsor: Laval University

Sex: All

Age: 65+

Code: NCT07607899

Recruiting

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NIRAF-camera Versus Conventional Surgery in Preoperative Imaging Negative Primary Hyperparathyroidism

for
Primary Hyperparathyroidism
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18+

Code: NCT07812649

Recruiting
New

Robotic Adrenalectomy With Versus Without Indocyanine Green Fluorescence Imaging

for
Adrenalectomy
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18+

Code: NCT07813247

Recruiting
New

A First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of HMB-003 in Healthy Volunteers

for
Healthy Adult Participants
Location: San Antonio TX
Sponsor: Hemab ApS

Sex: All

Age: 18 - 50

Code: NCT07798505

Phase1, Recruiting
New

A Phase 2 Study of NT-101 Topical in Patients With Wet AMD

for
Wet Age Related Macular Degeneration
Location: Bonita Springs FL, Erie PA, Tulsa OK
Sponsor: NexThera Co., Ltd.

Sex: All

Age: 50+

Code: NCT07811726

Phase2, Recruiting
New

A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease

for
Alzheimer's Disease
Location: Laurelton NY, Toronto, Maitland FL, Santa Ana CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 55 - 70+

Code: NCT07717411

Phase3, Recruiting
New

Immersive Virtual Reality for Older Adults in Long-Term Care Settings

for
Cognitive Impairment,
Location: Sainte-Marie, Quebec
Sponsor: Laval University

Sex: All

Age: 60+

Code: NCT07658287

Recruiting
New

Interventions to Enhance Quadriceps Output After ACLR

for
ACL
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18 - 40

Code: NCT07674784

Recruiting
New

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ONO-6414 Administered Orally in Healthy Adult Participants and Patients With Active Ulcerative Colitis

for
Ulcerative Colitis (UC)
Location: Miami FL
Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All

Age: 18 - 55

Code: NCT07749768

Phase1, Recruiting
New

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes

for
Diabetes Mellitus, Type 2
Location: Charlottesville VA, Boynton Beach FL, Tamarac FL,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 10 - 18

Code: NCT07282613

Phase3, Recruiting
New

Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)

for
Non Hodgkin Lymphoma, B-cell Non Hodgkin Lymphoma,
Location: Cleveland OH
Sponsor: Paolo Caimi, MD

Sex: All

Age: 18+

Code: NCT07225439

Phase1, Recruiting
Active & ResponsiveNew

Pacritinib in Participants With Metastatic Castrate-Resistant Prostate Cancer That Progressed on or After Prior Treatment With Androgen Receptor Signaling Inhibitors

for
Prostate Cancer
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: Male

Age: 18+

Code: NCT07226713

Phase2, Recruiting
Active & ResponsiveNew

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

for
Heart Failure With Preserved Ejection Fraction (HFpEF),
Location: The Bronx NY, Brooklyn NY, Kingston, Miami Lakes FL,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07761117

Phase3, Recruiting
New

Personalized Exercise Recommendations for Chronic Pelvic Pain Using Reinforcement Learning

for
Pelvic Pain, Endometriosis, Chronic Pelvic Pain
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: Female

Age: 18 - 55

Code: NCT07810218

Recruiting
New

Determine Maximum Tolerated Dose, Safety, and Tolerability of Rhenium (186Re) in Pediatric Recurrent, Refractory or Progressive Ependymoma and High-Grade Glioma

for
Ependymoma, High Grade Gliomas
Location: Chicago IL
Sponsor: Cerenome

Sex: All

Age: 6 - 21

Code: NCT07061626

Phase1, Recruiting
New

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Crinecerfont in Participants With Classic Congenital Adrenal Hyperplasia (CAH) Who Are Less Than 4 Years Old

for
Congenital Adrenal Hyperplasia
Location: Hartford CT, Atlanta GA, Ann Arbor MI, Indianapolis IN,
Sponsor: Neurocrine Switzerland GmbH

Sex: All

Age: 0 - 3

Code: NCT07536269

Phase2, Recruiting