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Study to Assess Safety and Immunogenicity of an Egg-based H5N8 Influenza Vaccine at Multiple Dose Levels Adjuvanted With Matrix-M in Healthy Participants 18 Years of Age and Above.

for
Healthy Volunteers, Influenza
Location: Charlottesville VA, Rochester NY, Coral Gables FL,
Sponsor: Sanofi

Sex: All

Age: 18+

Code: NCT07779408

Phase1, Phase2, Recruiting
New

Effects of Pork Protein on Recovery Following Simulated Fireground Activity

for
Exercise Recovery, Physical Performance Parameters,
Location: Huntsville TX, Fort Worth TX
Sponsor: Sam Houston State University

Sex: All

Age: 18 - 60

Code: NCT07819565

Recruiting
New

Testing the Combination of Anti-Cancer Drugs, Botensilimab (AGEN1181) and Balstilimab (AGEN2034), After Standard Treatment for Colorectal Cancer, Combat Trial

for
Colorectal Adenocarcinoma, Stage II Colorectal Cancer AJCC v8,
Location: New Orleans LA, Houston TX
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07551596

Phase2, Recruiting
New

Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First Relapse

for
Recurrent Multiple Myeloma, Refractory Multiple Myeloma
Location: Ottawa IL, Bloomington IL, Decatur IL, Peru IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06948084

Phase2, Recruiting
New

A Study to Investigate PORT-77 Oral Dosing Compared With Placebo in Participants With Erythropoietic Protoporphyria (EPP) or X-linked Protoporphyria (XLP)

for
Erythropoietic Protoporphyria (EPP),
Location: Cincinnati OH, Huntington Beach CA
Sponsor: Portal Therapeutics, Inc.

Sex: All

Age: 12+

Code: NCT07820085

Phase2, Phase3, Recruiting

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New

Defining the Ablative Dose for Y-90 TARE

for
HCC - Hepatocellular Carcinoma
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT07586046

Phase2, Recruiting
New

Level Up! (The Combined and Independent Effects of Exercise Training and Dietary Enhancement on Cardiometabolic Health in Adolescents With Obesity)

for
Obesity
Location: Little Rock AR
Sponsor: Arkansas Children's Hospital Research Institute

Sex: All

Age: 12 - 17

Code: NCT06848478

Recruiting
Active & ResponsiveNew

Within-Subject Comparison of Adipose Tissue Viability Following Liposuction

for
Liposuction
Location: Concord OH, Olympia WA
Sponsor: Apyx Medical

Sex: All

Age: 30 - 65

Code: NCT07820397

Recruiting
New

BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)

for
Small Cell Lung Cancer Extensive Stage, Small-cell Lung Cancer,
Location: East Brunswick NJ, Fairfax VA, Glendale CA,
Sponsor: SystImmune Inc.

Sex: All

Age: 18+

Code: NCT07625644

Phase3, Recruiting
Active & ResponsiveNew

A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors

for
Pediatric Tumor of CNS, Pediatric Tumor of Brain,
Location: Orange CA
Sponsor: Neonc Technologies, Inc.

Sex: All

Age: 5 - 18

Code: NCT06357377

Phase1, Recruiting
New

Study of Saroglitazar Magnesium for PBC Patients With Incomplete Response or Intolerant to UDCA Therapy

for
Primary Biliary Cholangitis
Location: Lakewood Rch FL
Sponsor: Zydus Therapeutics Inc.

Sex: All

Age: 18 - 70+

Code: NCT07424677

Phase3, Recruiting
Active & ResponsiveNew

A Study of the Safety and Efficacy of Prime Editing (PM577) in Participants With Wilson Disease (WD)

for
Wilson Disease, Wilson's Disease, Wilsons Disease
Location: San Antonio TX
Sponsor: Prime Medicine, Inc.

Sex: All

Age: 12+

Code: NCT07748403

Phase1, Phase2, Recruiting
Active & ResponsiveNew

Voices Illuminating Solutions for Outdoor Workers' Needs and Safety

for
Air Pollution Exposure
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT07713264

Recruiting
New

Testing the Investigational Agent Combination of Daratumumab, Bortezomib, and Dexamethasone Compared to the Usual Treatment of Cyclophosphamide, Bortezomib, and Dexamethasone in Newly Diagnosed Multiple Myeloma Patients With Kidney Failure

for
Myeloma Multiple
Location: Anchorage AK
Sponsor: Eastern Cooperative Oncology Group

Sex: All

Age: 18+

Code: NCT07085728

Phase2, Recruiting
New

A Study of 2141-V11 in People With Esophageal, Gastric, or Gastroesophageal Junction Adenocarcinoma

for
Esophageal Cancer, Advanced Esophageal Cancer, Gastric Cancer,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07818018

Phase1, Phase2, Recruiting
Active & ResponsiveNew

Development of a Noninvasive Metric to Measure Small Bowel Sensation - The Small Intestine Stress Test

for
Disorders of Gut Brain Interaction
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 70+

Code: NCT07817706

Recruiting
Active & ResponsiveNew

Haelan 951 for Menopause Symptoms in Peri- and Postmenopausal Women

for
Menopause, Menopause Hot Flashes, Menopause Related Conditions
Location: Kansas City MO
Sponsor: Spectrum Clinical Research, LLC

Sex: Female

Age: 45 - 65

Code: NCT07751029

Recruiting
Active & ResponsiveNew

Tensi+ for Treating Overactive Bladder

for
Overactive Bladder (OAB)
Location: New York NY, Toronto, Beverly Hills CA
Sponsor: Stimuli Technology

Sex: All

Age: 22+

Code: NCT07300904

Recruiting
New

A Phase 3 Trial of Inhaled Mosliciguat in PH-ILD (PHrontier)

for
Pulmonary Hypertension, Interstitial Lung Disease,
Location: Kissimmee FL, Louisville KY, Bend OR
Sponsor: Pulmovant, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07816185

Phase3, Recruiting
New

Randomized Controlld Trial of Dementia Education Resources for Action

for
Alzheimer's Disease and Related Dementia
Location: Fairfax VA
Sponsor: George Mason University

Sex: All

Age: 18+

Code: NCT07545577

Recruiting