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Study of the Safety and Effectiveness of Collagen Cross-Linking at an Irradiance of 9 mW/cm2 and 18 mW/cm2

for
Keratoconus, Corneal Ectasia
Location: Hoffman Estates IL
Sponsor: Robert Mack, M.D.

Sex: All

Age: 18 - 70+

Code: NCT02009709

Phase1, Recruiting

Smoking Cessation Following Psychiatric Hospitalization

for
Nicotine Dependence
Location: Austin TX
Sponsor: University of Texas at Austin

Sex: All

Age: 18+

Code: NCT02204956

Recruiting

Virtual 1-Session Spanish "Empowered Relief" Group Intervention for Chronic Pain

for
Chronic Pain
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT04546685

Recruiting

Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

for
Glioma
Location: Manhasset NY, Dallas TX, San Antonio TX
Sponsor: Plus Therapeutics

Sex: All

Age: 18+

Code: NCT01906385

Phase1, Phase2, Recruiting

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

for
Hormone Receptor Positive HER-2 Negative Breast Cancer,
Location: Boston MA, Horsham PA, Philadelphia PA, Richmond VA,
Sponsor: Puma Biotechnology, Inc.

Sex: All

Age: 18+

Code: NCT06369285

Phase2, Recruiting

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Stepped Approach to Reducing Risk of Suicide in Primary Care

for
Suicidal Ideation, Suicide, Attempted, Suicide Prevention
Location: Ashtabula OH, Painesville OH, Willoughby OH, Akron OH,
Sponsor: Cynthia Fontanella

Sex: All

Age: 12 - 17

Code: NCT06018285

Recruiting

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC

for
Metastatic Colorectal Cancer, Hepatocellular Carcinoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06553885

Phase2, Recruiting

Avapritinib With Decitabine in Patients With SM-AHN

for
Systemic Mastocytosis With an Associated Hematologic Neoplasm
Location: Tampa FL, Salt Lake City UT
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06327685

Phase1, Recruiting

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

for
Obstructive Sleep Apnea, Cognitive Decline
Location: New York NY, Pittsburgh PA, Tucson AZ
Sponsor: California Pacific Medical Center Research Institute

Sex: All

Age: 55 - 70+

Code: NCT05988385

Recruiting

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

for
Leukemia, Lymphoma, Myeloma, Myelodysplastic Syndromes,
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18+

Code: NCT05745285

Recruiting

A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors

for
Squamous Non-small-cell Lung Cancer,
Location: New Haven CT, Hackensack NJ, Fairfax VA, Louisville KY,
Sponsor: Alentis Therapeutics AG

Sex: All

Age: 18+

Code: NCT06747585

Phase1, Phase2, Recruiting

Striated Esophageal Motor Function Modulation in Health and Disease

for
Dysphagia, Esophageal
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18 - 70+

Code: NCT05708885

Recruiting

Reamer Irrigator Aspirator (RIA) vs Autogenous Iliac Crest Bone Graft (AICBG) for the Treatment of Non-unions

for
Nonunion of Bone Graft, Fractures Non Union
Location: Toronto
Sponsor: Unity Health Toronto

Sex: All

Age: 18 - 65

Code: NCT01382485

Recruiting

RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

for
Osteoporosis, Osteoporotic Fractures, Fragility Fracture
Location: Lebanon NH, The Bronx NY, New York NY, Durham NC,
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 50+

Code: NCT06455085

Recruiting
Active & Responsive

Tied Tube Trial in Glaucoma Surgery

for
Glaucoma Eye, Ahmed Glaucoma Valve Implantation
Location: Saint Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05685485

Recruiting

Hyperbaric Oxygen Therapy in Acute Ischemic Stroke Ischemic Stroke Recovery (Pro00061930)

for
Acute Ischemic Stroke
Location: New Orleans LA
Sponsor: LCMC Health

Sex: All

Age: 18+

Code: NCT06148285

Recruiting

The Effects of Peri-operative Pregabalin Administration on Post-operative Analgesia in Patients Undergoing Coronary Bypass Grafting

for
Postoperative Pain.
Location: Winnipeg
Sponsor: University of Manitoba

Sex: All

Age: 18 - 70

Code: NCT00623285

Phase3, Recruiting

Avocado Consumption, Nutrients in Human Milk, and Infant Cognitive Development

for
Breastfeeding, Exclusive
Location: Kannapolis NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18 - 40

Code: NCT06208085

Recruiting

The HIMALAYAS Trial and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Study: A Multicentre Randomized Controlled Trial

for
Heart Failure, Cardiotoxicity, Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18 - 45

Code: NCT05023785

Recruiting

PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases

for
Multiple Sclerosis, Alzheimer's Disease
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18 - 70+

Code: NCT02649985

Phase1, Phase2, Recruiting