Recruiting

Thyroid Tumors

Sponsor:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Code:

NCT00001160

Conditions

Hurthle Cell Thyroid Cancer

Tall Cell Variant Thyroid Cancer

Follicular Thyroid Cancer

Thyroid Cancer

Papillary Thyroid Cancer

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Interventions

68-Gallium Dotatate

Study Details

Brief summary:

Participants in this study will be patients diagnosed with or suspected to have a thyroid nodule or thyroid cancer.

The main purpose of this study is to further understand the methods for the diagnosis and treatment of thyroid nodules and thyroid cancer. Many of the test performed are in the context of standard medical care that is offered to all patients with thyroid nodules or thyroid cancer. Other tests are performed for research purposes. In addition, blood and tissue samples will be taken for research and genetic studies.

Conditions

Hurthle Cell Thyroid Cancer

Tall Cell Variant Thyroid Cancer

Follicular Thyroid Cancer

Thyroid Cancer

Papillary Thyroid Cancer

Study ID

NCT00001160

Start date

Jun 1, 1977

Status verified date

Aug 18, 2026

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

  • INCLUSION CRITERIA:

In order to be eligible to participate in this study, an individual must meet all of the following criteria:

1. Male or female, adults or children >= 6 months+.
2. Patients with known or suspected thyroid nodules and/or thyroid cancer.
3. At risk family members of patients who have a genetic susceptibility to developing thyroid cancer.

EXCLUSION CRITERIA:

An individual who meets any of the following criteria will be excluded from participation in this study:

1\. Serious underlying medical conditions that restrict diagnostic testing or therapy such as renal failure, congestive cardiac failure or active coexisting non-thyroid carcinoma requiring intervention before thyroid cancer is addressed.

Study Design

Enrollment

2500 participants

Anticipated

Interventions and Outcome Measures

Arms

thyroid cancer

Patients with thyroid cancer

thyroid nodules

Patients with thyroid nodules

Interventions

68-Gallium Dotatate

For evaluation risk/benefit evaluation

Primary outcome measure

  • Evaluation of thyroid cancer [ Time Frame: As clinically indicated ]
  • Evaluation of thyroid disorders [ Time Frame: As clinically indicated ]

Central Contacts and Locations

Central contacts

Padmasree Veeraraghavan, R.N.

(301) 451-7710padmasree.veeraraghavan@nih.gov

Joanna Klubo-Gwiezdzinska, M.D.

(301) 496-5052joanna.klubo-gwiezdzinska@nih.gov

Locations

National Institutes of Health Clinical Center

Recruiting

Bethesda, Maryland, United States, 20892

Contacts

For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

800-411-1222ccopr@nih.gov

More Information

Sponsor

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Last update posted

Aug 31, 2026

Last verified

Aug 18, 2026

Keywords

  • Thyroid Fine Needle Biopsy
  • Radioiodine
  • Dosimetry
  • Natural History

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) on 2026-08-31.