Recruiting

Movement Analysis

Sponsor:

NIH

Code:

NCT00001252

Conditions

Movement Disorder

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Accepted

Study Details

Brief summary:

This study will collect information on the different ways people control limb and body movements. This information will be used to develop a database on normal movements and adaptive movements of people who have diseases that affect the way they move. The database will serve as a tool to improve diagnosis and treatment of patients with movement-related problems.

Volunteers from one month old to old age who have normal movement patterns or who have developed different ways to perform movement tasks may be eligible for this study. A physician or physical therapist will screen candidates to determine their strength, flexibility and range of motion of joints.

Participants will be asked to perform movements such as walking, walking up or down stairs, standing quietly or reaching for an object or using treadmill. For the test, the arms and legs are wrapped with a soft, rubber-like material to which small plastic reflective balls are attached. A piece of firm material called a shell may be attached to the rubber sleeves or other areas of the body. Then the volunteer performs the specified task several times while special cameras record the movement. These cameras will record the positions of the reflective balls during movement and may show the person s face or body. Electrical activity in the muscles also may be measured, using small metal electrodes attached to the surface of the skin with an adhesive bandage.

Conditions

Movement Disorder

Study ID

NCT00001252

Start date

Mar 13, 1995

Status verified date

Feb 3, 2026

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Accepted

  • INCLUSION CRITERIA:

Individuals with neuromuscular disorders and Healthy Volunteers in order to be eligible to participate in this study, must meet all of the following criteria:

  • Children; One month old to 17 years of age

--In the case of infants and very young children, they need to be able to imitate or perform an action on cue (e.g., reach out for a toy that is presented or take steps if placed on a treadmill) based on the parent report if the subject is a child and physician observation during history and physical examination.
  • Adults; 18 years 99 years
  • In good general health as evidenced by medical history or diagnosed with impairment of neuromusculoskeletal system
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • Provision of signed and dated informed consent form
  • For those participants older than 5 years of age who have an abnormal gait pattern when walking as a result of a central nervous system injury, Dr. Alter will ask them or their guardian about their seizure history

EXCLUSION CRITERIA:

Individuals with neuromuscular disorders and Healthy Volunteers, who meets any of the following criteria will be excluded from participation in this study:

  • Individuals with pacemakers
  • Pregnancy
  • Adults unable to provide informed consent

Study Design

Enrollment

7500 participants

Anticipated

Interventions and Outcome Measures

Arms

healthy volunteer

Normal/healthy volunteers

Impaired volunteer

volunteers with impairments of the neuromusculoskeletal system.

Primary outcome measure

  • Gait Kinematics [ Time Frame: end of testing ]

Central Contacts and Locations

Central contacts

Locations

National Institutes of Health Clinical Center

Recruiting

Bethesda, Maryland, United States, 20892

Contacts

For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

800-411-1222ccopr@nih.gov

More Information

Sponsor

National Institutes of Health Clinical Center (CC)

Last update posted

Jul 10, 2026

Last verified

Feb 3, 2026

Keywords

  • Biomechanics
  • Kinesiology
  • Walking
  • Natural History

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by National Institutes of Health Clinical Center (CC) on 2026-07-10.