Recruiting

Parasitic Infections

Sponsor:

National Institute of Allergy and Infectious Diseases (NIAID)

Code:

NCT00001645

Conditions

Malaria

Intestinal Worms

GI Protozoa

Echiniococcus

Strongyloides

Eligibility Criteria

Sex: All

Age: 3+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The purpose of this study is to evaluate, treat and follow patients with parasitic infections.

People with a known or suspected parasitic infection who are at least 1 year old may be enrolled. This study does not involve any experimental treatments.

Participants will have a physical examination and laboratory tests on blood, stool, or urine. Blood samples may be collected at regular intervals, but no more than 450 ml (15 ounces) of blood will be drawn from adults, and no more than 7 ml (1-1/2 teaspoons) per kg (2.2 pounds) of body weight from children, in any 6-week period. Other tests may include x-rays, electrocardiogram (EKG), or tissue biopsy (surgical removal of a small tissue sample), depending on the individual s condition.

Patients may be offered treatment or may be referred to another study that is more appropriate for the problem. Any treatment provided in this study will be according to standard medical practice for the patient s specific medical problem. Patients responses to treatment will be evaluated at regularly scheduled clinic visits. The length of time between visits and the total duration of the study for a given individual will be determined by the study doctor, based on that person s medical condition.

...

Conditions

Malaria

Intestinal Worms

GI Protozoa

Echiniococcus

Strongyloides

Study ID

NCT00001645

Start date

Oct 10, 1998

Status verified date

Mar 11, 2026

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 3+

Healthy Volunteers: Not accepted

  • INCLUSION CRITERIA:

Age 3 or over.

Access to a primary medical care provider outside of the NIH

Clinical evidence suggestive of a parasitic infection

EXCLUSION CRITERIA:

Less than 3 years of age

No evidence suggestive of a parasitic infection

Study Design

Enrollment

800 participants

Anticipated

Interventions and Outcome Measures

Arms

Diarrhea GI parasite

Subjects infected with a GI parasite

Echinococcus

Subjects infected with echinococcus

Intestinal worm

Subjects infected with parasitic intestinal worm

Malaria

Subjects infected with malaria

Parasitic infection

Subjects infected with a parasitic infection that is not included in the other cohorts

Primary outcome measure

  • The Laboratory of Parasitic Diseases has been conducting studies of the diagnosis, treatment, and pathogenesis of wide variety of parasitic infections. [ Time Frame: 1 year ]

Central Contacts and Locations

Central contacts

Thomas B Nutman, M.D.

(301) 496-5399tnutman@mail.nih.gov

Locations

National Institutes of Health Clinical Center

Recruiting

Bethesda, Maryland, United States, 20892

Contacts

For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

800-411-1222ccopr@nih.gov

More Information

Sponsor

National Institute of Allergy and Infectious Diseases (NIAID)

Last update posted

Sep 1, 2026

Last verified

Mar 11, 2026

Keywords

  • Helminth Infection
  • Parasite
  • Known Parasitic Infection
  • Suspected Parasitic Infection
  • Natural History

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by National Institute of Allergy and Infectious Diseases (NIAID) on 2026-09-01.