Recruiting

Observational Study

Sponsor:

National Center for Research Resources (NCRR)

Code:

NCT00004374

Conditions

Amyloidosis

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

OBJECTIVES: I. Analyze prospectively the course of amyloid deposition in patients with primary, secondary, myeloma-associated, and hereditary amyloidosis.

II. Determine abnormalities of humoral and delayed-type hypersensitivity in these patients.

III. Identify prognostic factors in hereditary amyloidosis and develop tests for genetic defects associated with systemic amyloidosis.

IV. Diagnose familial amyloidotic polyneuropathy (FAP) prior to symptom onset. V. Validate the correlation of low serum prealbumin and retinol binding protein levels with amyloidosis in patients with FAP.

Conditions

Amyloidosis

Study ID

NCT00004374

Start date

Jan, 1979

Status verified date

Dec, 2003

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

PROTOCOL ENTRY CRITERIA:

--Disease Characteristics-- Systemic amyloidosis, i.e.: Primary, myeloma associated Secondary, e.g., associated with the following conditions: Rheumatoid arthritis Inflammatory bowel disease

Study Design

Enrollment

100 participants

Interventions and Outcome Measures

Central Contacts and Locations

Locations

Indiana University Cancer Center

Recruiting

Indianapolis, Indiana, United States, 46202-5265

Contacts

Merrill D. Benson

317-278-3426

More Information

Sponsor

National Center for Research Resources (NCRR)

Last update posted

Jun 24, 2005

Last verified

Dec, 2003

Keywords

  • amyloidosis
  • arthritis & connective tissue diseases
  • genetic diseases and dysmorphic syndromes
  • rare disease

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-23. This information was provided to ClinicalTrials.gov by National Center for Research Resources (NCRR) on 2005-06-24. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.