Recruiting

Observational Study

Sponsor:

National Center for Research Resources (NCRR)

Code:

NCT00005102

Conditions

DiGeorge Syndrome

Shprintzen Syndrome

Chromosome Abnormalities

Abnormalities, Multiple

Conotruncal Cardiac Defects

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

OBJECTIVES:

I. Determine the pattern of immunologic reconstitution in patients with T-cell compromise due to DiGeorge syndrome or velocardiofacial syndrome.

II. Determine any correlation between immunologic function in these patients and chromosome 22 deletion breakpoints.

III. Determine presence of sustained immunologic compromise in older patients.

Conditions

DiGeorge Syndrome

Shprintzen Syndrome

Chromosome Abnormalities

Abnormalities, Multiple

Conotruncal Cardiac Defects

Study ID

NCT00005102

Start date

Jan, 1995

Status verified date

Dec, 2003

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

  • Conotruncal cardiac lesion to be repaired by surgery AND Chromosome 22q11 deletion by FISH

Study Design

Enrollment

11 participants

Interventions and Outcome Measures

Central Contacts and Locations

Locations

Children's Hospital of Philadelphia

Recruiting

Philadelphia, Pennsylvania, United States, 19104

Contacts

Kathleen E. Sullivan

215-590-1697

More Information

Sponsor

National Center for Research Resources (NCRR)

Last update posted

Jun 24, 2005

Last verified

Dec, 2003

Keywords

  • DiGeorge syndrome
  • Shprintzen syndrome
  • cardiovascular and respiratory diseases
  • conotruncal cardiac defects
  • genetic diseases and dysmorphic syndromes
  • rare disease

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by National Center for Research Resources (NCRR) on 2005-06-24.