Recruiting

Observational Study

Sponsor:

National Center for Research Resources (NCRR)

Code:

NCT00006128

Conditions

Head Injuries, Closed

Eligibility Criteria

Sex: All

Age: 0 - 12

Healthy Volunteers: Not accepted

Study Details

Brief summary:

OBJECTIVES: I. Determine the relationship of closed head injury (CHI) severity, focal brain lesions, and the age at injury to the development of working memory, inhibition, and metacognitive skills in children or adolescents with CHI of varying severity.

II. Assess the development of working memory, inhibition, and metacognitive skills in relation to discourse functions, scholastic achievement, and adaptive behavior in these patients.

III. Determine the relationship between impaired inhibition, metacognitive skills, and the emergence of psychiatric disorder in these patients.

Conditions

Head Injuries, Closed

Study ID

NCT00006128

Start date

Jul, 1998

Status verified date

Dec, 2003

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 12

Healthy Volunteers: Not accepted

  • Study I: Closed head injury (CHI) that occurred at least 3 years ago
  • Study II: Recently diagnosed CHI
  • Both studies: Eligible if CHI resulted from acceleration, deceleration, or impact by a blunt object (e.g., motor vehicle accidents, pedestrian-vehicular injury, falls, assault except child abuse by caregiver) Preinjury emotional/behavioral problems allowed except mental retardation, autism, schizophrenia, or pervasive developmental disorder that would confound evaluation of cognitive function

Study Design

Enrollment

374 participants

Interventions and Outcome Measures

Central Contacts and Locations

Locations

Callier Center

Recruiting

Dallas, Texas, United States, 75235

Contacts

Sandra Chapman

214-905-3007

Baylor College of Medicine

Recruiting

Houston, Texas, United States, 77030

Contacts

Harvey S. Levin

713-798-4860

University of Texas- Houston Medical School

Recruiting

Houston, Texas, United States, 77030

Contacts

Linda Ewing-Cobbs

713-500-3888

Hospital for Sick Children

Recruiting

Toronto, Ontario, Canada, M5G 1X8

Contacts

Maureen Dennis

416-813-6658

More Information

Sponsor

National Center for Research Resources (NCRR)

Last update posted

Jun 24, 2005

Last verified

Dec, 2003

Keywords

  • neurologic and psychiatric disorders
  • rare disease

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by National Center for Research Resources (NCRR) on 2005-06-24.