Recruiting

Genetic Testing

Sponsor:

Indiana University

Code:

NCT00064870

Conditions

Alzheimer Disease

Late Onset Alzheimer Disease

Dementia

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The purpose of the Alzheimer's Disease Genetics Study is to identify the genes that are responsible for causing Alzheimer's Disease (AD). One of the ways in which the risk factor genes for late onset AD can be investigated is by identifying and collecting genetic material from families with multiple members diagnosed with AD or dementia.

Conditions

Alzheimer Disease

Late Onset Alzheimer Disease

Dementia

Study ID

NCT00064870

Start date

Jun, 2002

Status verified date

Apr, 2025

Completion date

Jul, 2026

Anticipated

Primary completion date

Jul, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Two living family members diagnosed with AD or other dementia with any age of onset
  • Biological samples available

  • Fresh blood, or
  • Immortalized lymphoblastic cell lines, or
  • 3-5 grams of frozen cerebral cortex; fixed samples are not accepted

Please note: this study does not include genetic counseling; because no personal identifying information such as name or date of birth is attached to samples, results of individual tests are not available to participants or family members.

Exclusion Criteria:

  • Does not meet inclusion criteria
  • Member of a family that was included in the National Institute of Mental Health AD Genetics Sib Pair collection

Study Design

Enrollment

10000 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Distribute biological specimens to qualified investigators for use in their research studies. [ Time Frame: Contact investigators annually for an update on progress and publication status. ]

Central Contacts and Locations

Central contacts

Study Coordinator

1-800-526-2839alzstudy@iu.edu

Locations

Participants are being recruited from all over the United States

Recruiting

Nationwide, Indiana, United States, 46202

Contacts

NCRAD Study Coordinator

800-526-2839alzstudy@iu.edu

More Information

Sponsor

Indiana University

Last update posted

Oct 1, 2025

Last verified

Apr, 2025

Keywords

  • Alzheimer disease
  • Late Onset Alzheimer disease risk factor genes
  • Genetics
  • Initiative
  • Dementia

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Indiana University on 2025-10-01.