Recruiting

Galantamine

Sponsor:

Rapoport, Alan, M.D.

Code:

NCT00219869

Conditions

Post-Traumatic Headache

Head Trauma,Closed

Retention Disorders,Cognitive

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Interventions

Galantamine

Study Details

Brief summary:

Most patients with CPTH present with additional major cognitive, behavioral and somatic problems. Most drugs used currently have a negative influence on cognition. Therefore, treatment strategies addressing both the headache and cognitive disturbances in patients with CPTH are necessary. (CPTH; Chronic Post Traumatic Headache).

Conditions

Post-Traumatic Headache

Head Trauma,Closed

Retention Disorders,Cognitive

Study ID

NCT00219869

Start date

Jul, 2005

Status verified date

Sep, 2005

Completion date

Aug, 2005

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

Age range 18-75 CPTH according to ICHD-2 Fertile woman using adequate birth control Willing and able to give informed consent Willing and able to complete the entire course of the study to comply with study instructions Stable does of preventive medication

-

Exclusion Criteria:

Subject is pregnant or lactating Significant medical or psychiatric disease Previous failure to 4 or more adequate trials of preventive medication Patient on non-stable dose of medication used to prevent CPTH

-

Study Design

Enrollment

30 participants

Allocation

Non randomized

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Interventions

Galantamine

Primary outcome measure

  • Primary Headache Efficacy Measure; number of pain free days after 3 months [ Time Frame: undefined ]

Central Contacts and Locations

Central contacts

Lori L Flanagan, RN

203-322-2748lc@nech.net

Kathy Diomede, RN

203-322-2748kd@nech.net

Locations

The New England Center for Headache

Recruiting

Stamford, Connecticut, United States, 06902

Contacts

Lori Flanagan, RN

203-322-2748lc@nech.net

Kathy Diomede

203-322-2748kd@nech.net

Principal Investigator:

Alan Rapoport, MD

More Information

Sponsor

Rapoport, Alan, M.D.

Last update posted

Sep 22, 2005

Last verified

Sep, 2005

Keywords

  • Post
  • Traumatic
  • Headache
  • Cognitive

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Rapoport, Alan, M.D. on 2005-09-22.