Recruiting

Ketamine with Lidocaine

Sponsor:

University Health Network, Toronto

Code:

NCT00221871

Conditions

Pain.

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Not accepted

Interventions

Different dosages of Ketamine

Study Details

Brief summary:

Ketamine added to Lidocaine can increase duration of pain relief following intraveonous regional anesthesia (IVRA). The purpose of this dose response study is to determine the minimum effective dosage of intravenous Ketamine, added to 3 mg/kg of Lidocaine. We anticipate that one dosage will provide us with the proper balance between sufficient anesthesia and minimal side effects.

Conditions

Pain.

Study ID

NCT00221871

Start date

Jan, 2004

Status verified date

Sep, 2005

Completion date

Jan, 2005

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Age: 18-70
2. Weight: 50-100 kg
3. ASA: I, II, III
4. Carpal tunnel syndrome surgery, tenolysis, ganglion removal or any peripheral hand surgery that can be done by IVRA.

Exclusion Criteria:

1. Contraindication to IVRA such as sickle cell disease.
2. Any known hypersensitivity reaction to Ketamine.
3. History of chronic pain or regular medication with analgesics.
4. History of opioid dependence.
5. Drug of alcohol abuse.
6. Psychiatric disorder.
7. Allergy to acetaminophen or codeine

Study Design

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Interventions

Different dosages of Ketamine

Central Contacts and Locations

Central contacts

Colin McCartney, MD

(416)603-5118colin.mccartney@uhn.on.ca

Locations

University Health Network

Recruiting

Toronto, Ontario, Canada, M5T2S8

Contacts

Filomena Valle-Leutri, BSc

(416)603-5800filomena.valle-leutri@uhn.on.ca

Principal Investigator:

Colin McCartney, MD

More Information

Sponsor

University Health Network, Toronto

Last update posted

Oct 11, 2006

Last verified

Sep, 2005

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University Health Network, Toronto on 2006-10-11.