Recruiting

DBT & Escitalopram

Sponsor:

Bronx VA Medical Center

Code:

NCT00255554

Conditions

Borderline Personality Disorder

Eligibility Criteria

Sex: All

Age: 18 - 60

Healthy Volunteers: Not accepted

Interventions

Dialectical Behavioral Therapy

Escitalopram

Study Details

Brief summary:

Subjects will receive six months of DBT, consisting of one 90-minute group and one 60-minute individual session per week as well as telephone availability of the individual therapist. Half the subjects will concurrently receive escitalopram while half will receive placebo, in a randomized double-blind design.

Conditions

Borderline Personality Disorder

Study ID

NCT00255554

Status verified date

Nov, 2005

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 60

Healthy Volunteers: Not accepted

Inclusion Criteria: Is a male or female between 18 and 60 who meets criteria for Borderline Personality Disorder and has been off psychotropic medications for at least 2 weeks (6 weeks for fluoxetine).

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Exclusion Criteria: Meets criteria for Schizophrenia, Bipolar Disorder, Mental Retardation, current or recent Substance Dependence or a current Major Depressive Episode. Subjects also should not currently be in individual psychotherapy. (Case management and work therapy programs are allowed.)

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Study Design

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Interventions

Dialectical Behavioral Therapy

Escitalopram

Primary outcome measure

  • Measures of impulsivity, aggression, affective impulsivity, immediate and delayed memory, and cognitive processing at baseline, 6 months and 9 months [ Time Frame: undefined ]

Central Contacts and Locations

Central contacts

Emily Hart

212-241-0441mpgroup@mssm.edu

Locations

Bronx VA Medical Center

Recruiting

Bronx, New York, United States, 10029

More Information

Sponsor

Bronx VA Medical Center

Last update posted

Nov 21, 2005

Last verified

Nov, 2005

Keywords

  • Borderline Personality Disorder
  • BPD
  • Dialectical Behavior Therapy
  • DBT
  • Escitalopram
  • Lexapro

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Bronx VA Medical Center on 2005-11-21.