Recruiting

Genetic Polymorphisms

Sponsor:

University of Pittsburgh

Code:

NCT00258570

Conditions

Pulmonary Fibrosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The purposes of this study are:

  • to determine if there are specific genetic traits that might explain why patients have developed pulmonary fibrosis;
  • to determine if specific genetic traits account for differing patterns of inflammation and scar tissue that has formed in the patient's lungs.

Conditions

Pulmonary Fibrosis

Study ID

NCT00258570

Start date

Jan, 2003

Status verified date

Aug, 2026

Completion date

Jul, 2035

Anticipated

Primary completion date

Jul, 2035

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • 18 years of age or older
  • Diagnosis of pulmonary fibrosis confirmed by physical examination, pulmonary function testing, chest X-ray, and computed tomography (CT) scans.
  • Adult patients who are seeking treatment at the Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease.

Exclusion Criteria:

  • Under 18 years of age
  • Non-fibrotic ILD

Study Design

Enrollment

2000 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF) [ Time Frame: Sample collection will occur up to 5 years based on the current rate of sample collection. ]

Central Contacts and Locations

Central contacts

Michelle F MacPherson, MAT

412-647-4537macphersonmj@upmc.edu

Michelle Meyers, BSN

412-692-2149meyersma@upmc.edu

Locations

University of Pittsburgh

Recruiting

Pittsburgh, Pennsylvania, United States, 15213

Contacts

Michelle F MacPherson, MAT

412-647-4537macphersonmj@upmc.edu

Michelle Meyers, BSN

412-692-2149meyersma@upmc.edu

Principal Investigator:

Kevin F. Gibson, M.D.

More Information

Sponsor

University of Pittsburgh

Last update posted

Aug 31, 2026

Last verified

Aug, 2026

Keywords

  • "Lung[A04.400]"

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Pittsburgh on 2026-08-31.