Recruiting

Observational StudyData and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

Sponsor:

Children's Hospital Medical Center, Cincinnati

Code:

NCT00267501

Conditions

Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease

Food Allergy

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of, clinical manifestations of, and spectrum of disease severity of eosinophilic inflammation in humans.

Conditions

Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease

Food Allergy

Study ID

NCT00267501

Start date

May, 2005

Status verified date

Sep, 2025

Completion date

Jan, 2050

Anticipated

Primary completion date

Jan, 2050

Anticipated

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Inclusion Criteria:

Signed informed consent obtained from the patient or parent/guardian. Assent will be obtained from all minors 11 years of age and older.
Carrying a diagnosis of eosinophilic gastrointestinal disease, eosinophilic inflammatory disease, or food allergy OR family member, or normal control

Study Design

Enrollment

5000 participants

Anticipated

Interventions and Outcome Measures

Central Contacts and Locations

Central contacts

Bliss Magella

513-636-7832 bliss.magella@cchmc.org

Locations

Cincinnati Children's Hospital Medical Center

Recruiting

Cincinnati, Ohio, United States, 45229-3039

Contacts

Bliss Magella

513-636-7832 bliss.magella@cchmc.org

Principal Investigator:

Marc E. Rothenberg, M.D., Ph.D.

More Information

Sponsor

Children's Hospital Medical Center, Cincinnati

Last update posted

Sep 17, 2025

Last verified

Sep, 2025

Keywords

Eosinophilic Disorders

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Children's Hospital Medical Center, Cincinnati on 2025-09-17.