Recruiting

Observational Study

Sponsor:

University of Pittsburgh

Code:

NCT00307281

Conditions

Emphysema

Chronic Obstructive Pulmonary Disease

Chronic Bronchitis

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The Comprehensive Lung Center (CLC) at the University of Pittsburgh Medical Center (UPMC Health System) provides patients with any type of breathing or lung disorder a full range of diagnostic and therapeutic services. The Emphysema/COPD Research Center (ECRC) is a specialty clinic, within this center, that attempts to advance the understanding of emphysema and to evaluate new therapies for patients with emphysema. The Emphysema Research Registry will enable pulmonary research physicians to: 1) gather information and create a research registry of people who have been diagnosed with emphysema; 2) utilize this research registry with the purpose of conducting research that attempts to advance the understanding of emphysema and to evaluate new therapies; and, 3) use the research registry to identify potential candidates for future research programs. These aims will be achieved by the collection of DNA (genetic material)for analysis and storage in addition to pulmonary function tests and other medical information.

Conditions

Emphysema

Chronic Obstructive Pulmonary Disease

Chronic Bronchitis

Study ID

NCT00307281

Start date

Aug, 2000

Status verified date

Sep, 2025

Completion date

Jul, 2030

Anticipated

Primary completion date

Jul, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Patients would be required to have COPD based on at least one of the following: clinical history, pulmonary function results, or radiographic results.

Exclusion Criteria:

  • none

Study Design

Enrollment

3000 participants

Anticipated

Interventions and Outcome Measures

Arms

Registry

10 pack year tobacco smoking history required, current or former smokers accepted.

Primary outcome measure

  • To gather information and create a research registry of people who have been diagnosed with emphysema and a control cohort of research participants without lung diseases, [ Time Frame: Indefinite ]

Central Contacts and Locations

Central contacts

Locations

University of Pittsburgh Emphysema/COPD Research Center

Recruiting

Pittsburgh, Pennsylvania, United States, 15213

Contacts

Principal Investigator:

Frank C. Sciurba, MD

More Information

Sponsor

University of Pittsburgh

Last update posted

Sep 25, 2025

Last verified

Sep, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Pittsburgh on 2025-09-25.