Recruiting

Topical Anesthetic

Sponsor:

University of Toronto

Code:

NCT00353041

Conditions

Pain

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Accepted

Interventions

lidocaine topical

Study Details

Brief summary:

This is a study of the effect of time on the effectiveness of topical anesthetics in the mouth. The Null Hypothesis is: Regardless of the time of application over a 10-minute period, there is no difference in the clinical effectiveness of the topical anesthetic 5% lidocaine on (a) the pain of needle stick insertion and (b) the pain of local anaesthetic administration.

Conditions

Pain

Study ID

NCT00353041

Start date

Jul, 2006

Status verified date

Jul, 2006

Completion date

Dec, 2006

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Accepted

Inclusion Criteria:

1. In good health (ASA 1 or ASA 2)
2. Weight between 40-100kg, inclusive.
3. Between ages 18-70, inclusive.
4. Informed consent

Exclusion Criteria:

1. ASA 3 or higher.
2. History of allergy to sulfites, lidocaine or mepivacaine.
3. Taking any analgesic 48hrs before testing, such as an NSAID, opioid, or acetaminophen.
4. Pregnancy.
5. Recent oral trauma.
6. Lack of informed consent.

Study Design

Enrollment

90 participants

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Educational/Counseling/Training

Interventions and Outcome Measures

Interventions

lidocaine topical

Primary outcome measure

  • pain [ Time Frame: undefined ]

Central Contacts and Locations

Central contacts

Jasdev Bhalla, BDS

4169794922drjasdev@yahoo.com

Locations

Faculty of Dentistry

Recruiting

Toronto, Ontario, Canada, M5G 1G6

Contacts

Jasdev Bhalla, BDS

416-979-4922drjasdev@yahoo.com

Principal Investigator:

Jasdev Bhalla, BDS

More Information

Sponsor

University of Toronto

Last update posted

Jul 17, 2006

Last verified

Jul, 2006

Keywords

  • topical
  • anesthetic
  • pain

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Toronto on 2006-07-17.