Recruiting

Observational Study

Sponsor:

Uniformed Services University of the Health Sciences

Code:

NCT00487487

Conditions

Post-Poliomyelitis Syndrome

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

Post-Poliomyelitis Syndrome (PPS) is the term describing the new problems affecting polio survivors many years after recovery from paralytic polio. Among the symptoms, fatigue is one of the most frequent and debilitating. In addition to physical incapacitation, the fatigue of PPS also affects mental function. The term "brain fatigue" is usually used by patients to express problems on the areas of attention, concentration, memory and clear thinking. Unfortunately, little is known about cognitive fatigue of PPS patients. This study is meant to examine if mental impairment is present in PPS patients and, if so, how it interferes on the self-function of patients. Patients will undergo an interview, clinical and neurological evaluation, and a battery of screening laboratory tests to make sure they are eligible for the study. Patients who qualify will undergo neuropsychometric tests in order to assay performance in the main areas of cognitive functioning. Through this organized approach we expect to be able to determine if mental fatigue is a significant problem affecting polio survivors, what areas are most affected, and how it may interfere with daily living.

Conditions

Post-Poliomyelitis Syndrome

Study ID

NCT00487487

Status verified date

Mar, 2007

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • 18 years of age or older
  • Be a survivor of poliomyelitis
  • Willing to attend two clinic visits for completion of screening procedures and required tests

Exclusion Criteria:

  • Suffer from medical conditions that can interfere with cognitive function, including stroke, traumatic brain injury, dementia (progressive memory loss), severe depression, psychosis or other psychiatric disorders, etc.

Study Design

Interventions and Outcome Measures

Central Contacts and Locations

Central contacts

Sandra Maxwell, RN

301-9840400smaxwell@usuhs.edu

Locations

Postpolio Syndrome Outpatient Research Office

Recruiting

Rockville, Maryland, United States, 20852

Contacts

Sandra Maxwell, RN

301-984-0400smaxwell@usuhs.edu

More Information

Sponsor

Uniformed Services University of the Health Sciences

Last update posted

Jun 18, 2007

Last verified

Mar, 2007

Keywords

  • Candidates for this study are survivors of paralytic poliomyelitis

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Uniformed Services University of the Health Sciences on 2007-06-18.