Recruiting

Genetics Study

Sponsor:

McGill University Health Centre/Research Institute of the McGill University Health Centre

Code:

NCT00523653

Conditions

Dilated Cardiomyopathy (DCM)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

blood test

Study Details

Brief summary:

Dilated cardiomyopathy (DCM) affects about 200,000 Canadians. Eighty percent of these cases are of unclear cause, often occuring in families. We believe that mutations in specific already-identified genes contribute to DCM in Quebec and that certain mutations may account for a significant proportion of cases due to the well-documented "founder effect". Two hundred patients with DCM followed in our Heart Function Clinic will be approached for one blood sample at their routine clinic visit to test this hypothesis. The samples will be tested in the Laboratory of Cardiovascular Genetics at the Royal Victoria Hospital.

Conditions

Dilated Cardiomyopathy (DCM)

Study ID

NCT00523653

Start date

Jan, 2008

Status verified date

Mar, 2008

Completion date

Dec, 2008

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Followed at MUHC Heart Function Centre
  • Documented EF of less than or equal to 35% and an enlarged heart with a left ventricular end-diastolic size of greater than 6 cm.
  • Patient's written consent

Exclusion Criteria:

  • Patients with a known underlying condition that results in a weakened and enlarged heart
  • Patients unable to read and understand the consent form
  • Patients who do not wish to participate

Study Design

Enrollment

200 participants

Anticipated

Interventions and Outcome Measures

Interventions

blood test

looking at DNA

Central Contacts and Locations

Central contacts

Nadia S Giannetti, MD

(514)934 1934nadia.giannetti@much.mcgill.ca

Locations

Royal Victoria Hospital

Recruiting

Montreal, Quebec, Canada, H3A 1A1

Contacts

Nadia Giannetti, MD

nadia.giannetti@muhc.mcgill.ca

More Information

Sponsor

McGill University Health Centre/Research Institute of the McGill University Health Centre

Last update posted

Mar 19, 2008

Last verified

Mar, 2008

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by McGill University Health Centre/Research Institute of the McGill University Health Centre on 2008-03-19.