Recruiting

Observational StudyRisk Factors That Increase the Chance of Developing Primary Graft Dysfunction After Lung Transplantation

Sponsor:

University of Pennsylvania

Code:

NCT00552357

Conditions

Primary Graft Dysfunction

Lung Transplantation

Eligibility Criteria

Sex: All

Age: 13 - 68

Healthy Volunteers: Not accepted

Study Details

Brief summary:

Primary graft dysfunction (PGD) is a severe lung complication that can occur in the days after lung transplant surgery. This study will analyze blood samples to determine if high levels of certain chemicals may increase the risk of developing PGD after a lung transplant.

Conditions

Primary Graft Dysfunction

Lung Transplantation

Study ID

NCT00552357

Start date

Dec, 2007

Status verified date

Jul, 2026

Completion date

Jun, 2027

Anticipated

Primary completion date

Jun, 2027

Anticipated

Eligibility Criteria

Sex: All

Age: 13 - 68

Healthy Volunteers: Not accepted

Inclusion Criteria:

Undergoing lung or combined heart and lung transplantation

Exclusion Criteria:

Undergoing combined organ transplantation other than heart and lung transplantation

Study Design

Enrollment

1150 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

Primary graft dysfunction, defined by the ISHLT criteria [ Time Frame: Measured within 72 hours following transplantation ]

Central Contacts and Locations

Central contacts

E.J. Demissie, MSN

215-573-4767

Locations

University of Pennsylvania

Recruiting

Philadelphia, Pennsylvania, United States, 19104

More Information

Sponsor

University of Pennsylvania

Last update posted

Jul 22, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Pennsylvania on 2026-07-22.