Recruiting

Observational Study

Sponsor:

Memorial Sloan Kettering Cancer Center

Code:

NCT00579566

Conditions

Sarcoma

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Interventions

Specimen protocol

Study Details

Brief summary:

The purpose of this study is to study normal and sarcoma cells. To study these cells we need to have human tissue. You will be having or have already had a procedure to remove tissue. We would like to use some of this tissue. We will use it for laboratory studies on the diagnosis,behavior and treatment of sarcoma. We will perform an extensive analysis of your samples. We will only use extra tissue left over after all needed testing has been done or remove an additional small amount of tissue if you are having a biopsy. We will also take blood samples before and/or after your procedure to measure biochemical factors that may help us predict the behavior of sarcoma.

Conditions

Sarcoma

Study ID

NCT00579566

Start date

Jun, 2002

Status verified date

Jul, 2026

Completion date

Jun, 2027

Anticipated

Primary completion date

Jun, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • All patients with known or suspected sarcoma who will have or have had tissue removed for therapeutic or diagnostic purposes.
  • Patients will be entered without preference for any particular racial/ethnic group or gender.
  • Patients may have received prior hormonal therapy, cytotoxic chemotherapy, irradiation, immunotherapy or surgical therapy.
  • Tissue specimens must be large enough in quantity to allow routine pathologic analysis, with the research laboratory specimen removed from the residual specimen, which would otherwise be discarded. Optimal tissue amounts for snap freeze: Core biopsy - 2 tissue cores Incisional biopsy- 0.5 to 1.5 grams Resected sarcoma specimen- 1.0 to 50 grams depending on size of specimen Normal fat or muscle tissue - 0.5 to 4.0 grams (if available from resected sarcoma specimen) Optimal tissue amounts for RNA later Core biopsy - 2 tissue cores Incisional biopsy- 30 mg (three 3 x 3 x 3 mm cubes) Resected sarcoma specimen - 30 mg (three 3 x 3 x 3 mm cubes) Normal fat or muscle tissue - 30 mg (three 3 x 3 x 3 mm cube

Exclusion Criteria:

\- None

Study Design

Enrollment

3000 participants

Anticipated

Interventions and Outcome Measures

Arms

1

Sarcoma patients undergoing core biopsy, incisional biopsy or definitive surgical resection for soft tissue masses of extremity, trunk or retroperitoneum

Interventions

Specimen protocol

The research specimen will be obtained from the residual specimen that would otherwise be discarded per usual hospital procedure.

Primary outcome measure

  • establish and maintain a specimen bank and sarcoma cell line resource [ Time Frame: 2 years ]

Central Contacts and Locations

Central contacts

Samuel Singer, MD

212-639-2940

Locations

Memorial Sloan Kettering Basking Ridge (Consent and Follow-Up)

Recruiting

Basking Ridge, New Jersey, United States, 07920

Contacts

Samuel Singer, MD

212-639-2940

Memorial Sloan Kettering Monmouth (Consent and Followup)

Recruiting

Middletown, New Jersey, United States, 07748

Contacts

Samuel Singer, MD

212-639-2940

Memorial Sloan Kettering Bergen (Consent and Follow up)

Recruiting

Montvale, New Jersey, United States, 07645

Contacts

Sam Singer, MD

212-639-2940

Memorial Sloan Kettering Commack (Consent and Follow-Up)

Recruiting

Commack, New York, United States, 11725

Contacts

Samuel Singer, MD

212-639-2940

Memorial Sloan Kettering Westchester (Consent and Followup)

Recruiting

Harrison, New York, United States, 10604

Contacts

Samuel Singer, MD

212-639-2940

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

Recruiting

New York, New York, United States, 10065

Contacts

Samuel Singer, M.D.

212-639-2940

Principal Investigator:

Samuel Singer, M.D.

Memorial Sloan Kettering Nassau (Consent and Followup)

Recruiting

Rockville Centre, New York, United States, 11553

Contacts

Sam Singer, MD

212-639-2940

More Information

Sponsor

Memorial Sloan Kettering Cancer Center

Last update posted

Jul 30, 2026

Last verified

Jul, 2026

Keywords

  • Biochemical Determinants
  • Molecular Determinants

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Memorial Sloan Kettering Cancer Center on 2026-07-30.