Recruiting

Observational StudyGenetic and Environmental Risk Factors for Hemorrhagic Stroke

Sponsor:

State University of New York at Buffalo

Code:

NCT00682695

Conditions

Stroke

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The purpose of this study is to find risk factors for hemorrhagic stroke.

Conditions

Stroke

Study ID

NCT00682695

Start date

Jan 1, 2025

Status verified date

Jul, 2026

Completion date

Dec 31, 2029

Anticipated

Primary completion date

Dec 31, 2029

Anticipated

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

Age 18 or older
Resident (6 months or longer) within the recruitment center
Fulfillment of the criteria for spontaneous ICH
No evidence of trauma, brain tumor/metastases or infectious processes as a cause of the hemorrhage
Ability of the patient or legal representative to provide consent for an interview, blood pressure determinations and DNA sampling

Exclusion Criteria:

Study Design

Enrollment

1000 participants

Anticipated

Interventions and Outcome Measures

Arms

Participants who have had a hemorrhagic stroke at University of Maryland, University of Cincinnati, Massachusetts General Hospital, Duke University, Columbia University and University of Chicago Illinois, age 18 years or greater. Ability of the patient or legal representative to provide informed consent. Racial/ethnic category meets one of the following: African American, Caucasian or Hispanic.

Healthy volunteers who are matched to the study cases with hemorrhagic stroke within +/- 5 years of age, same gender and same race.

Primary outcome measure

Perform deep DNA sequencing of Chr 1q22 [ Time Frame: Ongoing to be completed at the end of June 2021 ]

Central Contacts and Locations

Central contacts

Lee A Gilkerson, RN, BSN

513-558-6140 Lee.gilkerson@uc.edu

Locations

Baptist Health Louisville

Recruiting

Louisville, Kentucky, United States, 40207

Contacts

Karin Cryan

5022595564 karin.cryan@BHSI.COM

Principal Investigator:

Ranjit Bagga, MD

University of Maryland

Recruiting

Baltimore, Maryland, United States, 21201

Contacts

Tiffany Watson

410-706-1902 tiwatson@som.umaryland.edu

Principal Investigator:

Steven Kittner, MD

Massachusetts General Hospital

Recruiting

Boston, Massachusetts, United States, 02114

Contacts

Christina Kourkoulis

617-726-5358 CKOURKOULIS@PARTNERS.ORG

Principal Investigator:

Jonathan R, MD

Duke University

Recruiting

Durham, North Carolina, United States, 27710

Contacts

Andreea Podgoreanu

919-681-4054 andrea.podgoreanu@duke.edu

Principal Investigator:

Michael L James, MD

University of Cincinnati

Recruiting

Cincinnati, Ohio, United States, 45267

Contacts

Lee A Gilkerson, RN, BSN

513-558-6140 Lee.gilkerson@uc.edu

Principal Investigator:

Daniel Woo, MD

More Information

Sponsor

State University of New York at Buffalo

Last update posted

Jul 2, 2026

Last verified

Jul, 2026

Keywords

stroke
brain attack
hemorrhagic stroke
risk factors

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by State University of New York at Buffalo on 2026-07-02.