Recruiting

Genetic Testing

Sponsor:

Albert Einstein College of Medicine

Code:

NCT00707694

Conditions

Extreme Longevity

Eligibility Criteria

Sex: All

Age: 65+

Healthy Volunteers: Accepted

Study Details

Brief summary:

We believe extreme longevity is due to specific genes which function to delay aging and prevent disease. The purpose of the research is to identify the genes/mutations associated with healthier aging; to understand the biological functions of these genes/mutations; and to develop therapies to replicate these preservative genetic activities in individuals who do not have the genetic profile for longevity.

Conditions

Extreme Longevity

Study ID

NCT00707694

Start date

Jul, 1998

Status verified date

Dec, 2025

Completion date

Dec, 2032

Anticipated

Primary completion date

Dec, 2032

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 65+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Ashkenazi Jewish, age 95+,
  • Offspring of person age 95+,
  • Offspring of parents who died age 70 or younger.

Exclusion Criteria:

  • Non-Ashkenazis

Study Design

Enrollment

2000 participants

Anticipated

Interventions and Outcome Measures

Arms

Probands

Ashkenazi Jews ages 95 and older

Offspring

Ashkenazi Jewish offspring of Ashkenazi Jewish parent(s) who lived to at least the age of 95

Controls

Ashkenazi Jewish people with no family history of longevity

Central Contacts and Locations

Central contacts

Tina Gao

718-839-7176tina.gao@einsteinmed.edu

Locations

Private Homes

Recruiting

New York, New York, United States

Contacts

Wanda I Guzman, BA

718-430-3838WANDA.GUZMAN@EINSTEINMED.EDU

Hebrew Home Riverdale

Recruiting

Riverdale, New York, United States, 10471

Contacts

Charlotte Dell, LMSW

718-581-1139

More Information

Sponsor

Albert Einstein College of Medicine

Last update posted

Jan 2, 2026

Last verified

Dec, 2025

Keywords

  • 95 years of age and older

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Albert Einstein College of Medicine on 2026-01-02.