Recruiting

Active Knee Prosthesis

Sponsor:

Providence VA Medical Center

Code:

NCT00771589

Conditions

Amputation

Eligibility Criteria

Sex: All

Age: 18 - 50

Healthy Volunteers: Accepted

Interventions

Active Knee Prosthesis

Study Details

Brief summary:

The purpose of this study is to develop a robust, low-power, stable, and light weight, active knee prosthetic device that can dramatically increase gait symmetry and walking economy of a transfemoral amputee during walking.

State of the art prosthetic knees can be classified into three main classes: a) mechanically passive, b) variable-damping, and c) powered. Although the devices within each of these classes offer some advantages for above-knee amputees, their overall performance still presents some deficiencies. Artificial knees in the first two groups are predominantly damping devices, incapable of providing positive power output. Moreover, current powered prostheses are heavy and inefficient in their energy consumption, and/or they have a limited range of motion. To overcome such inadequacies, we have designed a novel prosthetic knee device with a biomimetic approach.

The design of the active knee prosthesis is inspired by the antagonistic muscle anatomy of the human knee joint. This device mimics the synergistic muscle activity at the knee using a double series-elastic actuator (SEA) system that resembles the major mono-articular muscle groups that help flex and extend the knee joint. The agonist-antagonist SEA knee architecture will allow for precise force control of the knee joint, mimicking the spring-like behavior of the human knee, as well as providing adequate energy for forward progression of the body. The SEA has been previously developed and tested on legged robots. Also, the SEA has been successfully applied to the development of an actuated ankle-foot orthoses (AAFO) at MIT AI Lab.

The mechanical architecture of the active knee prosthesis allows for independent engagement of flexion and extension tendon-like, series springs for the control of joint position and impedance, as well as net joint torque. Furthermore, this architecture permits a joint rotation with near zero friction, allowing the controller to take advantage of the passive dynamics of the system, thus, augmenting the overall energetic efficiency of the system.

Conditions

Amputation

Study ID

NCT00771589

Start date

May, 2008

Status verified date

Oct, 2008

Completion date

Apr, 2009

Anticipated

Primary completion date

Jan, 2009

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 50

Healthy Volunteers: Accepted

Inclusion Criteria:

  • They will be experienced at prosthesis ambulation
  • Capacity of ambulation at least at a K3 level (i.e. having the ability or potential for ambulation with variable cadence).

Exclusion Criteria:

  • Amputee participants will be generally healthy and will have no other musculoskeletal problems or any known cardiovascular, pulmonary or neurological disorders.

Study Design

Enrollment

10 participants

Anticipated

Intervention Model

Single group

Primary purpose

Diagnostic

Interventions and Outcome Measures

Arms

experimental: Prosthesis

Motorized External Knee prosthesis for above knee amputees. Comprised of agonist and antagonist actuators to mimic behavior of knee joint during locomotion.

Interventions

Active Knee Prosthesis

Motorized External Knee Prosthesis for above knee amputees.

Central Contacts and Locations

Central contacts

Locations

Biomechatronics Research Group, MIT

Recruiting

Cambridge, Massachusetts, United States, 02142

Contacts

Principal Investigator:

Hugh Herr, Ph.D.

LIfestyle Prosthetics & Orthotics

Recruiting

North Andover, Massachusetts, United States, 01845

Contacts

More Information

Sponsor

Providence VA Medical Center

Last update posted

Oct 13, 2008

Last verified

Oct, 2008

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Providence VA Medical Center on 2008-10-13.