Recruiting

Angiogenesis Analysis

Sponsor:

UCLA

Code:

NCT00842283

Conditions

Dermatologic Diseases

Eligibility Criteria

Sex: All

Age: 16+

Healthy Volunteers: Accepted

Interventions

skin tissue sample

Study Details

Brief summary:

The researchers believe that pro-angiogenic factors are upregulated in a wide range of dermatologic diseases, including port wine stains, hemangiomas, angiofibromas, Kaposi's sarcoma, angiosarcoma, scars, rosacea, and psoriasis. Select specimens may undergo genetic analysis to investigate underlying molecular pathways associated with dysregulated angiogenesis in cutaneous disease.

Biospecimens, either previously obtained or newly collected from dermatologic conditions, will be analyzed for angiogenic markers. Discarded skin tissue from surgical or biopsy procedures may also be used, including both diseased and non-diseased tissue from the same donor. Some specimens may also undergo genetic analysis to investigate underlying molecular pathways.

De-identified data such as age, sex, race, cause of death, lesion location, and description will be recorded. Currently, specimens are limited to clinically diagnosed lesions not typically biopsied, or lesions already confirmed by prior biopsy.

Conditions

Dermatologic Diseases

Study ID

NCT00842283

Start date

Nov, 2008

Status verified date

Apr, 2026

Completion date

Dec, 2028

Anticipated

Primary completion date

Dec, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 16+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 16 years of age or older.
  • willing to have a skin biopsy

Exclusion Criteria:

  • under 16 years of age
  • unable to carry out instructions

Study Design

Enrollment

85 participants

Anticipated

Interventions and Outcome Measures

Arms

dermatologic diseases

skin tissue sample

Interventions

skin tissue sample

skin tissue sample

Primary outcome measure

  • Factors in dermatologic diseases. [ Time Frame: up to 4 weeks ]

Central Contacts and Locations

Central contacts

Hanna Kim

949-824-2251hhkim3@uci.edu

Locations

Beckman Laser Institute and Medical Clinic

Recruiting

Irvine, California, United States, 92697

Contacts

Hanna Kim

949-824-2251hhkim3@uci.edu

Principal Investigator:

Kristen Kelly, MD

Dermatology Clinic at Gavin Herbert Eye Institute

Recruiting

Irvine, California, United States, 92697

Contacts

Hanna Kim

949-824-2251hhkim3@uci.edu

Principal Investigator:

Kristen M Kelly, MD

More Information

Sponsor

University of California, Irvine

Last update posted

Apr 13, 2026

Last verified

Apr, 2026

Keywords

  • dermatologic diseases

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of California, Irvine on 2026-04-13.