Recruiting

Genetic Studies

Sponsor:

Stanford University

Code:

NCT01034033

Conditions

Breast Cancer

Ovarian Cancer

Gynecologic Cancers

Ovarian/Peritoneal/Fallopian Cancer

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The purpose of this study is to try to understand the biology of development of breast, ovarian, fallopian tube, peritoneal or endometrial cancer from persons at high genetic risk for these diseases. The influence of environmental factors on cancer development in individuals and families will be studied. The efficacy of treatments for these diseases will be evaluated.

Conditions

Breast Cancer

Ovarian Cancer

Gynecologic Cancers

Ovarian/Peritoneal/Fallopian Cancer

Study ID

NCT01034033

Start date

Aug, 2001

Status verified date

May, 2026

Completion date

Jan, 2099

Anticipated

Primary completion date

Jan, 2099

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

I. Women who have a high risk of developing breast or ovarian cancer due to a known germline mutation in the BRCA1/2, PTEN, CDH1, or TP53 cancer susceptibility genes, or due to strong family history of either breast or ovarian cancer, in the absence of known cancer susceptibility gene mutation.

II. Women who are approaching surgery for resection of a pelvic mass, which is considered suspicious for neoplasia by radiologic or clinical criteria; such women may or may not also meet criteria for inclusion in group I.

Study Design

Enrollment

3300 participants

Anticipated

Interventions and Outcome Measures

Central Contacts and Locations

Central contacts

Meredith Mills

(650) 724-5223bluett@stanford.edu

Locations

Stanford University School of Medicine

Recruiting

Stanford, California, United States, 94305

Contacts

Meredith Mills

650-724-5223bluett@stanford.edu

Principal Investigator:

James M Ford

More Information

Sponsor

Stanford University

Last update posted

May 18, 2026

Last verified

May, 2026

Keywords

  • quality of life

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Stanford University on 2026-05-18.