Recruiting

Observational Study

Sponsor:

Stanford University

Code:

NCT01048281

Conditions

Stomach Cancer

Gastro-Esophageal(GE) Junction Cancer

Gastric (Stomach) Cancer

Esophageal Cancer

Gastrointestinal Stromal Tumor (GIST)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Blood draw

Tissue tumor biopsy

Study Details

Brief summary:

Our research of the biology of upper gastrointestinal cancers involves the study of tissue samples and cells from biopsies of persons with gastric or esophageal cancer or blood samples from upper gastrointestinal cancer patients and persons at high inherited risk for these cancers. We hope to learn the role genes and proteins play in the development of gastric and esophageal cancer.

Conditions

Stomach Cancer

Gastro-Esophageal(GE) Junction Cancer

Gastric (Stomach) Cancer

Esophageal Cancer

Gastrointestinal Stromal Tumor (GIST)

Study ID

NCT01048281

Start date

Aug, 2002

Status verified date

Dec, 2025

Completion date

Jan, 2099

Anticipated

Primary completion date

Jan, 2099

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Over 18
2. Diagnosed with gastric or esophageal cancer OR at an increased hereditary risk for upper GI cancer

Exclusion Criteria:

1. Under 18
2. No family or personal history of gastric or esophageal cancer

Study Design

Enrollment

100 participants

Anticipated

Interventions and Outcome Measures

Interventions

Blood draw

Tissue tumor biopsy

Primary outcome measure

  • p53 activity by routine pathologic analysis [ Time Frame: time of collection ]
  • NER activity by routine pathologic analysis [ Time Frame: time of collection ]

Central Contacts and Locations

Central contacts

Locations

Stanford University School of Medicine

Recruiting

Stanford, California, United States, 94305

Contacts

Principal Investigator:

James M Ford

More Information

Sponsor

Stanford University

Last update posted

Dec 18, 2025

Last verified

Dec, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Stanford University on 2025-12-18.