Recruiting

Ablation Technique

Sponsor:

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Code:

NCT01113788

Conditions

Atrial Flutter

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

tricuspid isthmus imaging with Cartosound

Study Details

Brief summary:

The investigators propose a third hypothesis based on the anatomic observations made in pathological studies. The investigators hypothesize that the anatomic architecture determines the functional properties of the TV-IVC isthmus. As a result,

• Muscular bundles are preferential routes of conduction through the TV-IVC isthmus. The isthmus acts like a series of discreet conduction routes rather than as a sheet of tissue.

The muscular bundles form selective targets for ablation and therefore the entire anatomic line need not be ablated. This has direct implications for ablation of the isthmus.

Conditions

Atrial Flutter

Study ID

NCT01113788

Start date

Mar, 2010

Status verified date

Apr, 2010

Completion date

Dec, 2010

Anticipated

Primary completion date

Dec, 2010

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients must be over 18 years of age provided written informed consent documented atrial flutter by ECG , holter monitor or TTM

Exclusion Criteria:

  • previous atrial flutter ablation non isthmus dependent atrial flutter prior right atrial surgery

Study Design

Enrollment

15 participants

Anticipated

Interventions and Outcome Measures

Arms

imaging

imaging with usual catheter/fluoroscopy, no cartosound

Interventions

tricuspid isthmus imaging with Cartosound

tricuspid isthmus imaging with Cartosound

Primary outcome measure

  • observational including ablation lesion number, ablation time in minutes, fluoroscopic [ Time Frame: 12 months ]

Central Contacts and Locations

Central contacts

Allan Skanes, MD

519-663-3746askanes@uwo.ca

Cathy Bentley

519-685-8500-32835cbentl@uwo.ca

Locations

London Health Sciences Center

Recruiting

London, Ontario, Canada, N6A 5A5

More Information

Sponsor

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Last update posted

Apr 30, 2010

Last verified

Apr, 2010

Keywords

  • atrial flutter, tricuspid isthmus, ablation

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's on 2010-04-30.