Recruiting

Observational Study

Sponsor:

University of Pittsburgh

Code:

NCT01163578

Conditions

Solid Organ Transplantation

Bone Marrow Transplantation

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The objective of this study is to evaluate whether certain proteins, expressed in biological tissues can indict a better understanding of the effect of drugs that are used to treat rejection, and of processes leading to rejection and rejection-free outcomes.

Conditions

Solid Organ Transplantation

Bone Marrow Transplantation

Study ID

NCT01163578

Start date

Mar, 2005

Status verified date

Aug, 2026

Completion date

Mar, 2030

Anticipated

Primary completion date

Mar, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Recipients of abdominal, thoracic and bone marrow allografts that are receiving inpatient and outpatient follow-up with routine laboratory tests at the University of Pittsburgh Medical Center.
  • All Ages
  • Subject or parents are able to read and understand the informed consent

Exclusion Criteria:

  • Subjects and/or their parents who are unable to read and understand informed consent.

Study Design

Enrollment

1200 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Rejection [ Time Frame: 90 day post transplantation (clinical severity) ]

Central Contacts and Locations

Central contacts

Morgan L Paul, BSN

412-692-8472Morgan.Paul2@upmc.edu

Daniel Pieratt, MPA

412-692-6692pierattdw@upmc.edu

Locations

Children's Hospital of Pittsburgh of UPMC

Recruiting

Pittsburgh, Pennsylvania, United States, 15224

Contacts

Morgan L Paul, BSN

412-692-8472Morgan.Paul2@upmc.edu

Daniel Pieratt, MPA

412-692-6692pierattdw@upmc.edu

Principal Investigator:

Rakesh Sindhi, MD

More Information

Sponsor

University of Pittsburgh

Last update posted

Aug 10, 2026

Last verified

Aug, 2026

Keywords

  • Transplantation
  • Rejection

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Pittsburgh on 2026-08-10.