Recruiting

Selective Laser Trabeculoplasty

Sponsor:

University of Toronto

Code:

NCT01209975

Conditions

Glaucoma

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Interventions

Selective Laser Trabeculoplasty

Study Details

Brief summary:

The purpose of this study is to assess retinal blood flow and vascular reactivity in patients with newly diagnosed primary open angle glaucoma pre- and post-primary Selective Laser Trabeculoplasty(SLT). Canon Laser Blood Flowmeter will be used for the assessment of retinal blood flow.

Conditions

Glaucoma

Study ID

NCT01209975

Start date

Nov, 2008

Status verified date

Sep, 2010

Primary completion date

Nov, 2011

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Age 40-75 years (Male or Female)
2. Best corrected visual acuity of at least 20/40
3. No previous treatment for glaucoma
4. Ametropia less than ±6.0 DS and ±2.5 DC)
5. Non-smoker
6. No cardiovascular/respiratory disorders

Exclusion Criteria:

1. Past history of diabetes and cerebrovascular accident
2. Vascular occlusive disease affecting the ocular circulation such as: diabetic retinopathy, retinal vein occlusion and retinal artery occlusion
3. Previous intraocular surgery
4. Ocular media opacities limiting the use of the imaging tests

Study Design

Enrollment

12 participants

Anticipated

Interventions and Outcome Measures

Arms

untreated glaucoma patients

We will evaluate the blood flow before and after Selective Laser Trabeculoplasty in patients with primary open angel glaucoma.

Interventions

Selective Laser Trabeculoplasty

Patient will have selective laser trabeculoplasty as the first treatment for glaucoma. This treatment will be dictated clinically, since we do not assign the interventions.

Primary outcome measure

  • blood flow [ Time Frame: before and two-week after SLT ]

Central Contacts and Locations

Central contacts

Tien Wong

416-603-5694twong@uhnres.utoronto.ca

Locations

Toronto Western Hospital

Recruiting

Toronto, Ontario, Canada, M5T2S8

Contacts

Tien Wong

416-603-5694twong@uhnres.utoronto.ca

More Information

Sponsor

University of Toronto

Last update posted

Sep 28, 2010

Last verified

Sep, 2010

Keywords

  • blood flow
  • glaucoma
  • SLT

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Toronto on 2010-09-28.