Recruiting

Genomic Predictors

Sponsor:

Brigham and Women's Hospital

Code:

NCT01258231

Conditions

Heart; Dysfunction Postoperative, Cardiac Surgery

Genetic Predisposition to Disease

Atrial Fibrillation

Myocardial Infarction

Heart Failure

Eligibility Criteria

Sex: All

Age: 20 - 70+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure.

Patients undergoing heart surgery at Brigham and Women's Hospital and Texas Heart Institute are eligible to participate.

Conditions

Heart; Dysfunction Postoperative, Cardiac Surgery

Genetic Predisposition to Disease

Atrial Fibrillation

Myocardial Infarction

Heart Failure

Study ID

NCT01258231

Start date

Aug, 2000

Status verified date

Aug, 2024

Completion date

Aug, 2030

Anticipated

Primary completion date

Aug, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 20 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Undergoing heart surgery
  • Willing to provide consent

Exclusion Criteria:

  • Enrolled in a concurrent drug or device trial that precludes concurrent enrollment

Study Design

Enrollment

4000 participants

Anticipated

Interventions and Outcome Measures

Arms

Cardiac surgery

Adult patients undergoing cardiac surgery

Primary outcome measure

  • Mortality (i.e. number of participants who are deceased during postoperative day 0 up to year 5) [ Time Frame: Day of procedure to year 5 ]

Central Contacts and Locations

Locations

UT Southwestern Medical Center

Recruiting

Dallas, Texas, United States, 75390-9068

Contacts

Amanda A Fox, MD

214-648-8018amanda.fox@utsouthwestern.edu

Principal Investigator:

Amanda A Fox, MD

More Information

Sponsor

Brigham and Women's Hospital

Last update posted

Aug 22, 2024

Last verified

Aug, 2024

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Brigham and Women's Hospital on 2024-08-22.