Recruiting

Observational Study

Sponsor:

University of Arizona

Code:

NCT01421420

Conditions

Alzheimer's Disease

Mild Cognitive Impairment

Age-Related Memory Disorders

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The main objective of this research project is to provide a comprehensive clinical database of patients with Alzheimer's disease (AD) and other forms of dementia, individuals with mild cognitive impairment (MCI), and age-matched normal controls. The study will also attempt to identify cognitively normal individuals at genetically defined risk for Alzheimer's disease through genetic screening.

All participants are seen annually. Autopsies to establish diagnoses in patients with dementia, patients with mild MCI, and cognitively normal elderly control subjects will also be conducted.

Conditions

Alzheimer's Disease

Mild Cognitive Impairment

Age-Related Memory Disorders

Study ID

NCT01421420

Start date

Jul, 2001

Status verified date

Jan, 2015

Completion date

Jul, 2025

Anticipated

Primary completion date

Dec, 2024

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Accepted

Inclusion Criteria:

For patients with MCI, or dementia, the presence of cognitive deficits including memory, language, and executive function.

Exclusion Criteria:

Presence of non-neurological medical conditions interfering with cognition.

Study Design

Enrollment

900 participants

Anticipated

Interventions and Outcome Measures

Arms

Alzheimer's Disease

Mild Cognitive Impairment

Other forms of Dementia, not AD

Normal Elderly Individuals

Primary outcome measure

  • Neuropsychological Test Scores [ Time Frame: Up to 20 years ]

Central Contacts and Locations

Locations

University of Arizona, University Medical Center

Recruiting

Tucson, Arizona, United States, 85724

Contacts

Kim Corley, B.A.

520-626-3746kgcorley@email.arizona.edu

Principal Investigator:

Steven Z Rapcsak, M.D.

More Information

Sponsor

University of Arizona

Last update posted

Jun 12, 2015

Last verified

Jan, 2015

Keywords

  • Alzheimer's
  • Dementia
  • Mild Cognitive Impairment

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Arizona on 2015-06-12.