Recruiting

SCAD Registry

Sponsor:

Mayo Clinic

Code:

NCT01429727

Conditions

Spontaneous Coronary Artery Dissection

SCAD

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The primary goal of this project is to describe the clinical and physiologic characteristics of Spontaneous Coronary Artery Dissections (SCAD) in order to increase awareness, understanding, treatment and prevention of a potentially fatal cardiovascular event.

This study will be a retrospective and prospective review of medical course and current health of men and women with SCAD.

Conditions

Spontaneous Coronary Artery Dissection

SCAD

Study ID

NCT01429727

Start date

Jul, 2011

Status verified date

Jan, 2026

Completion date

Dec, 2030

Anticipated

Primary completion date

Dec, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Individuals who have been cared for at Mayo Clinic with a diagnosis of SCAD
  • SCAD in women who are pregnant or within 12 months postpartum at the time of SCAD
  • SCAD in individuals who self-identify as a member of a racial or ethnic group that is currently underrepresented in the registry. This would include anyone who identifies as: Black/African American, Asian, American Indian or Alaska Native, Native Hawaiian or Other Pacific Islander, and any race with Hispanic ethnicity
  • SCAD in a man
  • SCAD in persons younger than 30 years of age
  • SCAD within the past 2 weeks (acute)
  • SCAD patient enrolling into any other Mayo Clinic SCAD Research Study
  • SCAD in individuals who have a relative that has had a SCAD event

Persons with history of SCAD who are interested in participating in the study but do not meet the updated inclusion criteria will not be enrolled at this time. However, they will be given the option to share their contact information in order to be invited to future Mayo Clinic SCAD studies.

Study Design

Enrollment

2500 participants

Anticipated

Interventions and Outcome Measures

Arms

SCAD Registry

Individuals who have experienced at least one episode of spontaneous coronary artery dissection.

Primary outcome measure

  • Descriptive Data [ Time Frame: Continuous time frame following index event for 2-10 years from study contact date. ]

Central Contacts and Locations

Central contacts

Susan Milbrandt

507-266-3180mayoscad@mayo.edu

Locations

Mayo Clinic

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

Susan Milbrandt

507-266-3180mayoscad@mayo.edu

Principal Investigator:

Marysia S Tweet, M.D., M.S.

More Information

Sponsor

Mayo Clinic

Last update posted

Jan 23, 2026

Last verified

Jan, 2026

Keywords

  • Spontaneous coronary artery dissection
  • SCAD
  • coronary artery disease
  • myocardial infarction
  • coronary dissection

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-01-23.