Recruiting
Phase 2

Transcranial Direct Current Stimulation

Sponsor:

University of Southern California

Code:

NCT01460771

Conditions

Childhood Onset Dystonias

Eligibility Criteria

Sex: All

Age: 4 - 21

Healthy Volunteers: Not accepted

Interventions

TDCS (Transcranial Direct-current Stimulation)

sham TDCS (Transcranial Direct-current Stimulation)

Study Details

Brief summary:

The investigators hypothesize that transcranial direct current stimulation over the motor cortex will reduce muscle overflow and improve hand function in children with primary or secondary dystonia.

Conditions

Childhood Onset Dystonias

Study ID

NCT01460771

Start date

Sep, 2011

Status verified date

May, 2014

Completion date

Sep, 2017

Anticipated

Primary completion date

Sep, 2017

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 4 - 21

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • dystonia affecting one or both hands
  • age 4 to 21 years

Exclusion Criteria:

  • metal implants in the head
  • inability to cooperate with instructions

Study Design

Enrollment

100 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Treatment

Active Transcranial Direct Current Stimulation (TDCS) at 1mA or highest tolerated current

sham comparator: sham

inactive Transcranial Direct current stimulation (TDCS) at 0mA

Interventions

TDCS (Transcranial Direct-current Stimulation)

active TDCS

sham TDCS (Transcranial Direct-current Stimulation)

TDCS at 0mA

Primary outcome measure

  • Hand muscle overflow [ Time Frame: 10 minutes post- transcranial Direct-current Stimulation (TDCS) ]

Central Contacts and Locations

Central contacts

Aprille Tongol

213-740-1317tongol@usc.edu

Diana Ferman

310-425-2342dferman@usc.edu

Locations

University of Southern California

Recruiting

Los Angeles, California, United States, 90089

Principal Investigator:

Terence D Sanger, MD, PhD

More Information

Sponsor

University of Southern California

Last update posted

May 22, 2014

Last verified

May, 2014

Keywords

  • childhood dystonia

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Southern California on 2014-05-22.