Recruiting

BiorepositoryCaris Biorepository Research Protocol

Sponsor:

Caris Science, Inc.

Code:

NCT01499394

Conditions

Cancer

Early Detection of Cancer

Minimal Residual Disease

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The Biorepository for Caris Life Sciences is designed for the purpose of making quality biospecimens and associated clinical data available for research studies related to advancing precision medicine and improving care for patients.

The Caris Biorepository is a repository of prospectively collected biological specimens and associated clinical and demographic data gathered from multiple sources to be stored, used and shared for research. Caris Life Sciences will maintain the data and specimens and will control access to and use of the information and specimens by multiple individuals for multiple purposes which may evolve over time.

Conditions

Cancer

Early Detection of Cancer

Minimal Residual Disease

Study ID

NCT01499394

Start date

Nov, 2010

Status verified date

Jan, 2026

Completion date

Nov, 2035

Anticipated

Primary completion date

Nov, 2030

Anticipated

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

18 years of age or older
Capacity to provide informed consent

Exclusion Criteria:

Due to the complexity of state and federal requirements governing the participation of prisoners in research, prisoners-patients will not be approached for participation in the Caris Biorepository.
Minor subjects will not be included in the Caris Biorepository, as it is possible biospecimens and data may be stored beyond the time limitations of assent and it may be impracticable to re-consent these subjects once they become adults.
Individuals who lack the capacity to give informed consent

Study Design

Enrollment

100000 participants

Anticipated

Interventions and Outcome Measures

Arms

Normal

Donor samples reflective of a "normal" non-disease state

Newly Diagnosed Pan-Cancer Collection

Donor samples derived from treatment naïve patients with newly diagnosed solid tumors.

Early Detection Collection

Donor samples reflective of a population at increased risk for developing cancer.

Advanced Stage Cancer Collection

Donor samples derived from individuals with advanced stage cancer.

Minimal Residual Disease Collection

Donor samples obtained from individuals with a history of malignancy who are currently free of active disease

Primary outcome measure

Develop biorepository that ensures molecular integrity and clinical relevance of quality human biospecimens and associated clinical data. [ Time Frame: 35 years ]
Implement release of specimens from biorepository for testing [ Time Frame: 35 years ]

Central Contacts and Locations

Central contacts

Mary Baker

carisresearch@carisls.com

Locations

University of South Alabama

Recruiting

Mobile, Alabama, United States

Contacts

Tiffany Fulford

251-445-3276 tnfulford@health.southalabama.edu

Southwest Medical Imaging

Recruiting

Scottsdale, Arizona, United States

Contacts

Emily Crampton

480-425-4055 ECrampton@esmil.com

St. Bernards Medical Center

Recruiting

Jonesboro, Arkansas, United States

Contacts

Dashae King

870-207-8157 dlking@sbrmc.org

CARTI Cancer Center

Recruiting

Little Rock, Arkansas, United States

Contacts

Jesse Byrd

501-561-2205 Jesse.Byrd@Carti.com

ObjectiveHealth - ARcare Center for Clinical Research

Recruiting

Little Rock, Arkansas, United States

Contacts

Cynthia Whitcomb

501-214-0372 Cynthia.Whitcomb@objective.health

Lee Memorial Health System

Recruiting

Fort Myers, Florida, United States

Contacts

Juliana Turner

239-343-9660 juliana.turner@leehealth.org

Cancer Care of North Florida

Recruiting

Lake City, Florida, United States

Contacts

Natalie Espenship

386-755-1655 Natalie.Espenship@cancercareofnorthflorida.com

Advent Health

Recruiting

Orlando, Florida, United States

Contacts

Corina Mattix

407-303-1327 Corina.Mattix@AdventHealth.com

The University of South Florida

Recruiting

Tampa, Florida, United States

Contacts

Brittney Short

727-612-4026 bborresen@tgh.org

Cleveland Clinic Florida

Recruiting

Weston, Florida, United States

Contacts

Brianna Hammond

954-487-2257 HAMMONB7@ccf.org

Phoebe Putney Memorial Hospital

Recruiting

Albany, Georgia, United States, 31701

Contacts

Cathy Shoemaker, OCN CBCN

229-312-0354

Emory University

Recruiting

Atlanta, Georgia, United States

Contacts

Sharon Egbue-Ojirogbe

404-778-8027 cegbueo@emory.edu

Augusta University Research Institute

Recruiting

Augusta, Georgia, United States

Contacts

Alexander Ward

706-721-1623 ALWARD@augusta.edu

Cancer Center of Middle Georgia

Recruiting

Dublin, Georgia, United States

Contacts

Audrey Bryan

478-272-8266 research@ccmgeorgia.com

Hope and Healing Cancer Services

Recruiting

Hinsdale, Illinois, United States

Contacts

Ava Baftirovska

630 560 0121 abaftirovska@hopenheal.care

CHRISTUS - St. Frances Cabrini Hospital

Recruiting

Alexandria, Louisiana, United States

Contacts

Crystal Dubois

318-528-5137 crystal.dubois2@christushealth.org

Tulane University

Recruiting

New Orleans, Louisiana, United States

Contacts

Priya Bhandari

504-988-6053 pbhandari@tulane.edu

CHRISTUS - Highland Medical Center

Recruiting

Shreveport, Louisiana, United States

Contacts

Thea Spencer

318-681-6007 thea.spencer@christushealth.org

Mercy Medical Center

Recruiting

Baltimore, Maryland, United States

Contacts

Rhiannon Kim

410-951-7908 rkim1@mdmercy.com

Sinai Hospital of Baltimore

Recruiting

Baltimore, Maryland, United States

Contacts

Pamela Nickoles

410-601-6120 Pnickole@lifebridgehealth.org

Hattiesburg Clinic

Recruiting

Hattiesburg, Mississippi, United States

Contacts

Gloria Simmons

601-288-2494 Gloria.Simmons@forrestgeneral.com

Jackson Oncology Associates

Recruiting

Jackson, Mississippi, United States

Contacts

Teresa Davis

601-974-5547 tdavis@jacksononcology.com

University of Mississippi Medical Center

Recruiting

Jackson, Mississippi, United States

Contacts

Tanya Robinson

601-815-2123 trobinson13@umc.edu

ObjectiveHealth - Premier Health Research

Recruiting

Sparta, New Jersey, United States

Contacts

Lori Walsh

862-294-0418 Lori.Walsh@objective.health

CHRISTUS - St. Vincent Regional Cancer Center

Recruiting

Santa Fe, New Mexico, United States

Contacts

MiQuela Gutierrez

505-913-8822 Miquela.Gutierrez@stvin.org

St. Lawrence Health System

Recruiting

Potsdam, New York, United States

Contacts

McKenna Boula

315-261-6319 McKenna.Boula@rochesterregional.org

National Translational Research Group

Recruiting

Ridge, New York, United States

Contacts

Stella Smaragdas

631-675-5103 ssmaragdas@nycancer.com

Altru Health System

Recruiting

Grand Forks, North Dakota, United States

Contacts

Alexis Tatum

701-780-1563 ATATUM@altru.org

NEO Urology Associates

Recruiting

Boardman, Ohio, United States

Contacts

Tina Picino

330-729-9214 tpicino@neourology.com

Great Lakes Medical Research

Recruiting

Cleveland, Ohio, United States

Contacts

Cortney Vazquez

216-372-0505 cvazquez@thectnx.com

Bend Memorial Clinic

Recruiting

Bend, Oregon, United States

Contacts

Madison Cox

541-706-5339 mklinskicox@summithealth.com

Clinical Biotechnology Research Institute at RSFH

Recruiting

Charleston, South Carolina, United States

Contacts

Aindrea Maddray

843-724-2204 Aindrea.Maddray@rsfh.com

Spartanburg Regional Health Services

Recruiting

Spartanburg, South Carolina, United States

Contacts

Kamara Mertz-Rivera

864-560-6104 kmertz-Rivera@gibbscc.org

West Cancer Center

Recruiting

Germantown, Tennessee, United States

Contacts

Melissa Smith

901-683-0055 msmith@WESTCLINIC.com

ObjectiveHealth - Amarillo Premier Research

Recruiting

Amarillo, Texas, United States

Contacts

Lauren Kuehler

806-641-0256 Lauren.Kuehler@objective.health

CHRISTUS - St. Michael's Health

Recruiting

Texarkana, Texas, United States

Contacts

Kimberly Everett

903-614-6885 kimberly.everett@christushealth.org

CAMC Clinical Trials

Recruiting

Charleston, West Virginia, United States, 25304

Contacts

Kristi Sutphin

304-388-9945 kristi.sutphin@CAMC.org

Mercy Health

Recruiting

Janesville, Wisconsin, United States

Contacts

Ashli Huppert

608-756-6695 ahuppert@mhemail.org

More Information

Sponsor

Caris Science, Inc.

Last update posted

Jan 21, 2026

Last verified

Jan, 2026

Keywords

Caris Biorepository
MCED
Early Detection
MRD
Pan-Cancer

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Caris Science, Inc. on 2026-01-21.