Recruiting

Prostacyclin

Sponsor:

Fertility Specialists of Houston

Code:

NCT01549171

Conditions

Pregnancy

Eligibility Criteria

Sex: Female

Age: 20 - 39

Healthy Volunteers: Not accepted

Interventions

Iloprost

normal saline

Study Details

Brief summary:

Human fallopian tube secretes high concentration of prostacyclin. Fallopian tube is the site for early embryo development. The effect of prostacyclin on human early embryo development is waiting to be clarified. The study hypothesis is prostacyclin can enhance early embryo development.

Conditions

Pregnancy

Study ID

NCT01549171

Start date

Jan, 2010

Status verified date

Mar, 2012

Completion date

Dec, 2013

Anticipated

Primary completion date

Nov, 2011

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 20 - 39

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • ART case

Exclusion Criteria:

  • age < 40
  • no pre-implantation genetic diagnosis procedure

Study Design

Enrollment

100 participants

Anticipated

Interventions and Outcome Measures

Arms

Iloprost

This is the study group with 1 uM Iloprost.

Control

This is the control group with vehicle (normal saline) only.

Interventions

Iloprost

supplement in culture medium during culture in the lab. The concentration is 1 uM.

normal saline

Supplement with vehicle only no Iloprost.

Primary outcome measure

  • Presence of embryo sac in uterus under ultrasound [ Time Frame: 5 weeks after embryo transfer ]

Central Contacts and Locations

Locations

Fertility Specialists of Houston

Recruiting

Houston, Texas, United States, 77054

Contacts

Wan-Song A Wun, Ph.D.

713-512-7680awun@obgynassociates.com

George M Grunert, M.D.

713-512-7760ggrunert@fshivf.com

More Information

Sponsor

Fertility Specialists of Houston

Last update posted

Mar 9, 2012

Last verified

Mar, 2012

Keywords

  • Human ART
  • Prostacyclin
  • Iloprost
  • Pregnancy

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Fertility Specialists of Houston on 2012-03-09.