Recruiting

Observational StudyNeuroblastoma Biology Study

Sponsor:

New Approaches to Neuroblastoma Therapy Consortium

Code:

NCT01587300

Conditions

Neuroblastoma

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

Medical scientists want to find better ways to treat neuroblastoma and to find ways to prevent the tumor from growing back. To do this, they need more information about the characteristics of neuroblastoma cells. Therefore, they want to study samples of neuroblastoma tissues and neuroblastoma and normal cells in the blood and bone marrow that may be related to the growth of neuroblastoma cells. Doctors and other medical scientists also want to find better ways to detect and measure neuroblastoma to improve the ability to follow the response of tumor cells to therapy.

Conditions

Neuroblastoma

Study ID

NCT01587300

Start date

Jul, 2011

Status verified date

Mar, 2026

Completion date

Dec, 2099

Anticipated

Primary completion date

Dec, 2099

Anticipated

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

Patients must be greater than or 31 days of age.
Patients must have had a diagnosis of high risk neuroblastoma either by histological verification of neuroblastoma and/or demonstration of tumor cells in the bone marrow with increased urinary catecholamines.
All patients with refractory or recurrent high risk neuroblastoma at NANT institutions are eligible regardless of disease status (including no measurable or evaluable tumor) as long as they undergo a disease evaluation and appropriate samples are submitted.
Additionally, all patients with high risk neuroblastoma without relapse treated at a NANT institution are eligible if undergoing a disease evaluation, as long as Children's Oncology Group specimens are prioritized.

Exclusion Criteria:

There are no exclusion criteria on this study.

Study Design

Enrollment

1000 participants

Anticipated

Interventions and Outcome Measures

Central Contacts and Locations

Central contacts

Araz Marachelian, MD

323-361-5687 amarachelian@chla.usc.edu

Locations

Children's Hospital Los Angeles

Recruiting

Los Angeles, California, United States, 90027-0700

UCSF Helen Diller Family Comprehensive Cancer Center

Recruiting

San Francisco, California, United States, 94115

Children Hospital of Colorado

Recruiting

Aurora, Colorado, United States, 80045

AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus

Recruiting

Atlanta, Georgia, United States, 30322

University of Chicago, Comer Children's Hospital

Recruiting

Chicago, Illinois, United States, 60637

Children's Hospital Boston

Recruiting

Boston, Massachusetts, United States, 02115

C.S Mott Children's Hospital

Recruiting

Ann Arbor, Michigan, United States, 48109

Cincinnati Children's Hospital Medical Center

Recruiting

Cincinnati, Ohio, United States, 45229-3039

Nationwide Children's Hospital

Recruiting

Columbus, Ohio, United States, 43205

Children's Hospital of Philadelphia

Recruiting

Philadelphia, Pennsylvania, United States, 19104-4318

Cook Children's Medical Center - Fort Worth

Recruiting

Fort Worth, Texas, United States, 76104

Seattle Children's Hospital

Recruiting

Seattle, Washington, United States, 98105

Hospital for Sick Children

Recruiting

Toronto, Ontario, Canada, M5G 1X8

More Information

Sponsor

New Approaches to Neuroblastoma Therapy Consortium

Last update posted

Mar 23, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by New Approaches to Neuroblastoma Therapy Consortium on 2026-03-23.