Recruiting

Fractional Laser Therapy

Sponsor:

University of Manitoba

Code:

NCT01619917

Conditions

Burn Scar

Eligibility Criteria

Sex: All

Age: 18 - 60

Healthy Volunteers: Not accepted

Interventions

Fractional Vascular Laser

Study Details

Brief summary:

While the literature tends to support the use of laser therapy in the management of burn scars, there is a definite lack of appropriately powered, randomized controlled trials. Laser therapy can be quite expensive when compared to other treatment modalities for burn scars, and while promising, its true usefulness has yet to be conclusively demonstrated. For this reason, our assessing the effects of fractional vascular lasers on burn scars. It has been hypothesized that the fractional vascular lasers work on mature scars to decrease scar formation, and the fractional laser works on scar that is quiescent to promote remodelling. The retexturing/ resurfacing of the laser theoretically can decrease the visibility of the mesh pattern created by meshed split thickness skin graft).

Objective:

To determine the benefit of fractional vascular laser treatment in improving burn scar height, texture, vascularity and pliability in late burn scars.

Conditions

Burn Scar

Study ID

NCT01619917

Start date

Nov 1, 2012

Status verified date

May, 2026

Completion date

Jul 1, 2028

Anticipated

Primary completion date

Jun 1, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 60

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • living in Winnipeg
  • burn scar 6-12 months old
  • Fitzpatrick skin type I-III
  • thermal burn scar on trunk or extremities

Exclusion Criteria:

  • open wound

Study Design

Enrollment

6 participants

Anticipated

Allocation

Randomized

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Proximal

location of the scar proximal to heart

experimental: Distal

location of scar distal to heart

Interventions

Fractional Vascular Laser

laser energy will be applied to one of 2 sites (proximal or distal) depending on randomization result

Primary outcome measure

  • reduction in scar appearance [ Time Frame: every 3 weeks to 15 weeks ]

Central Contacts and Locations

Central contacts

Justin Gawaziuk, MSc

2047893669jgawaziuk@hsc.mb.ca

Locations

University of Manitoba

Recruiting

Winnipeg, Manitoba, Canada, R3A 1R9

Contacts

Justin P Gawaziuk, MSc

2047873669jgawaziuk@hsc.mb.ca

Principal Investigator:

Sarvesh Logsetty, MD

More Information

Sponsor

University of Manitoba

Last update posted

May 14, 2026

Last verified

May, 2026

Keywords

  • burn
  • scar
  • laser
  • fractional
  • vascular

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Manitoba on 2026-05-14.