Recruiting

Stem Cells

Sponsor:

University of Nevada, Las Vegas

Code:

NCT01677520

Conditions

Breast Cancer

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The overall purpose of this study is to enhance identification and isolation of ADSCs and adipocytes, to find the optimum culturing conditions to increase growth and volume of grafts, and to study the effects of cryopreservation on ADSCs and adipocytes. Fat injections are used in aesthetic surgery but tend to disassemble over time. If the investigators can enhance growth and volume of fat in culture, the investigators could use fat grafts in reconstruction of cancer and traumatic injury defects with the patients own cultured fat cells and grafts.

Conditions

Breast Cancer

Study ID

NCT01677520

Start date

Mar, 2011

Status verified date

Jan, 2015

Completion date

Aug, 2018

Anticipated

Primary completion date

Aug, 2018

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • All adults (18-70 yrs) who have scheduled surgical lipectomy of the hips, abdomen, or thighs are prospective subjects for this study.

Exclusion Criteria:

  • Pregnant women will be excluded to protect the unborn child.

Study Design

Enrollment

240 participants

Anticipated

Interventions and Outcome Measures

Arms

18-30 yrs, 31-50 yrs, 51-70 yrs

No intervention

Primary outcome measure

  • Percent of Viable ADSCs [ Time Frame: Day of Surgery ]

Central Contacts and Locations

Central contacts

William A Zamboni, M.D.

702-671-2278wzamboni@medicine.nevada.edu

Shelley J Williams, M.S.

702-895-1445sjwilliams@medicine.nevada.edu

Locations

University of Nevada School of Medicine Patient Care Center

Recruiting

Las Vegas, Nevada, United States, 89102

Contacts

William A Zamboni, M.D.

wzamboni@medicine.nevada.edu

Karen Zamboni, BSRN

702-671-5118kzamboni@medicine.nevada.edu

Principal Investigator:

William A Zamboni, M.D.

More Information

Sponsor

University of Nevada, Las Vegas

Last update posted

Jan 9, 2015

Last verified

Jan, 2015

Keywords

  • adipose-derived stem cells
  • viable ADSCs
  • apoptosis
  • necrosis
  • cryopreservation

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Nevada, Las Vegas on 2015-01-09.