Recruiting

Ibuprofen vs. Liquid

Sponsor:

Albany Medical College

Code:

NCT01681667

Conditions

Pharyngitis

Eligibility Criteria

Sex: All

Age: 12 - 65

Healthy Volunteers: Not accepted

Interventions

Ibuprofen

Study Details

Brief summary:

Ibuprofen (also known as Advil or Motrin) is a medication that is known to reduce pain. It is also known that ibuprofen levels in the blood rise higher and faster if the medication is taken in liquid suspension. This study will attempt to determine if ibuprofen suspended in a liquid works to relieve sore throat pain faster than pills of ibuprofen. It will also determine whether patients with sore throat prefer to take pill or liquid form of the medication.

Conditions

Pharyngitis

Study ID

NCT01681667

Start date

Sep, 2013

Status verified date

Mar, 2014

Completion date

May, 2015

Anticipated

Primary completion date

May, 2015

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 12 - 65

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age greater than 12 years and less than 65 years
  • Weight > 40 kg
  • a provider order for ibuprofen to address pharyngitis pain.
  • Initial Numeric Pain Score > 6

Exclusion Criteria:

  • Known allergy or hypersensitivity to aspirin or NSAIDs
  • Inability to swallow pills
  • Inability to carry out informed consent in English
  • Inability to complete a visual analog pain scale
  • A concomitant order for another class of analgesic
  • Use of analgesic within 8 hours
  • Known 3rd trimester pregnancy
  • Significant medical conditions where participation would pose an unnecessary barrier to ongoing care.
  • Those taking opioid medications for more than 3 days
  • Weight < 40 kg

Study Design

Enrollment

100 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: ibuprofen

liquid ibuprofen 400mg compared to tablet ibuprofen 400mg

placebo comparator: sugar pill or liquid

Interventions

Ibuprofen

ibuprofen liquid 400mg vs. ibuprofen tablet 400mg

Primary outcome measure

  • Time of pain relief [ Time Frame: 1 hour ]

Central Contacts and Locations

Central contacts

Nancy Robak, RN, MPH

518-262-3773RobakN@mail.amc.edu

Locations

Albany Medical Center Emergency Department

Recruiting

Albany, New York, United States, 12204

Principal Investigator:

Wayne Triner, DO, MPH

More Information

Sponsor

Albany Medical College

Last update posted

Mar 12, 2014

Last verified

Mar, 2014

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Albany Medical College on 2014-03-12.