Recruiting

Radiation Therapy

Sponsor:

Massachusetts General Hospital

Code:

NCT01696721

Conditions

Pediatric Patients Treated With Radiation Therapy

Eligibility Criteria

Sex: All

Age: 0 - 21

Healthy Volunteers: Not accepted

Interventions

No intervention

Study Details

Brief summary:

In previous studies, Proton Beam Radiation Therapy (PBRT) has been found to show better results in treating patients with cancer, both because there is better control of where in the body the radiation is directed and because it is associated with less severe long term side effects. However, there is limited published data demonstrating these results. The goal of the Proton and Photon Consortium Registry (PPCR) is to enroll children treated with radiation in order to describe the population that currently receives radiation and better compare the short-term and long-term benefits of different types of radiotherapy. The data collected from this study will help facilitate research on radiation therapy and allow for collaborative research. The PPCR will collect demographic and clinical data that many centers that deliver radiation therapy already collect in routine operations.

Conditions

Pediatric Patients Treated With Radiation Therapy

Study ID

NCT01696721

Start date

Jul, 2012

Status verified date

May, 2026

Completion date

Dec, 2028

Anticipated

Primary completion date

Dec, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 21

Healthy Volunteers: Not accepted

Eligibility Criteria:

1. Patients treated with radiation therapy at one of the participating centers
2. Age < 22 at time of treatment start.
3. Patients may be enrolled regardless of previous local or systemic treatments received prior to enrollment in the PPCR.
4. Patients may be enrolled regardless of other current local or systemic treatments or disease extent.
5. Patients may be enrolled on the PPCR concurrently with another study or clinical trial.

Study Design

Enrollment

5000 participants

Anticipated

Interventions and Outcome Measures

Arms

Pediatric Patients Treated with Protons

Proton Radiation Therapy

Interventions

No intervention

Primary outcome measure

  • Establish Registry [ Time Frame: 2 years ]

Central Contacts and Locations

Central contacts

Torunn I Yock, MD

6177266876tyock@partners.org

Locations

Stanford University

Recruiting

Palo Alto, California, United States, 94304

Contacts

Susan Hiniker, MD

shiniker@stanford.edu

Principal Investigator:

Susan Hiniker, MD

California Protons Cancer Therapy Center

Recruiting

San Diego, California, United States, 92121

Contacts

Iain MacEwan, MD

iain.macewan@californiaprotons.com

Principal Investigator:

Iain MacEwan, MD

University of California San Francisco

Recruiting

San Francisco, California, United States, 94143

Contacts

Steve Braunstein, MD

Steve.Braunstein@ucsf.edu

Principal Investigator:

Steve Braunstein, MD

University of Florida Health Proton Therapy Institute

Recruiting

Jacksonville, Florida, United States, 32206

Contacts

Daniel Indelicato, MD

dindelicato@floridaproton.org

Principal Investigator:

Daniel Indelicato, MD

Emory University

Recruiting

Atlanta, Georgia, United States, 30308

Contacts

Bree Eaton, MD

brupper@emory.edu

Principal Investigator:

Bree Eaton, MD

Northwestern Medicine Chicago Proton Center

Recruiting

Warrenville, Illinois, United States, 60555

Contacts

Stephen Mihalcik, MD

stephen.mihalcik@nm.org

Principal Investigator:

Stephen Mihalcik, MD

Maryland Proton Treatment Center

Recruiting

Baltimore, Maryland, United States, 21201

Contacts

Young Kwok, MD

ykwok@umm.edu

Principal Investigator:

Young Kwok, MD

Massachusetts General Hospital

Recruiting

Boston, Massachusetts, United States, 02114

Contacts

Torunn I Yock, MD

617-726-6876tyock@partners.org

Principal Investigator:

Torunn I Yock, MD

Mayo Clinic

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

Nadia Laack, MD

Laack.nadia@mayo.edu

Principal Investigator:

Nadia Laack, MD

Washington University

Recruiting

St Louis, Missouri, United States, 63110

Contacts

Stephanie Perkins, MD

sperkins@wustl.edu

Principal Investigator:

Stephanie Perkins, MD

ProCure Proton Therapy Center- New Jersey

Recruiting

Somerset, New Jersey, United States, 08873

Contacts

Josephine Blume

Josephine.blume@nj.procure.com

Principal Investigator:

Suzanne Wolden, MD

New York Proton Center

Recruiting

New York, New York, United States, 10035

Contacts

Suzanne Wolden, MD

woldens@MSKCC.ORG

Principal Investigator:

Suzanne Wolden, MD

State University of New York Upstate Medical Center

Recruiting

Syracuse, New York, United States, 13210

Contacts

Paul Aridgides, MD

AridgidP@upstate.edu

Principal Investigator:

Paul Aridgides, MD

University of North Carolina

Recruiting

Chapel Hill, North Carolina, United States, 27514

Contacts

Dana Casey, MD

dana_casey@med.unc.edu

Principal Investigator:

Dana Casey, MD

The Ohio State University

Recruiting

Columbus, Ohio, United States, 43210

Contacts

Joshua Palmer, MD

Joshua.Palmer@osumc.edu

Principal Investigator:

Joshua Palmer, MD

Cincinnati Children's Proton Therapy Center

Recruiting

Liberty Township, Ohio, United States, 45044

Contacts

John Perentesis, MD

John.Perentesis@cchmc.org

Principal Investigator:

John Perentesis, MD

Oklahoma Proton Center

Recruiting

Oklahoma City, Oklahoma, United States, 73142

Contacts

John H Chang, MD

John.Chang@OKCProton.com

Principal Investigator:

John H Chang, MD

ProCure Proton Therapy Center- Oklahoma

Recruiting

Oklahoma City, Oklahoma, United States, 73142

Contacts

Jae Y Lee, MD, PhD

Jae.lee@procure.com

Principal Investigator:

Jae Y Lee, MD, PhD

University of Pennsylvania - Roberts Proton Therapy Center

Recruiting

Philadelphia, Pennsylvania, United States, 19104

Contacts

Christine Hill-Kayser, MD

hill@uphs.upenn.edu

Principal Investigator:

Christine Hill-Kayser, MD

MD Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Contacts

Arnold Paulino, MD

APaulino@mdanderson.org

Principal Investigator:

Arnold Paulino, MD

Texas Center for Proton Therapy

Recruiting

Irving, Texas, United States, 75063

Contacts

Victor Mangona, MD

Victor.Mangona@usoncology.com

Principal Investigator:

Victor Mangona, MD

University of Utah

Recruiting

Salt Lake City, Utah, United States, 84112

Contacts

Matthew Poppe, MD

Matthew.Poppe@hci.utah.edu

Principal Investigator:

Matthew Poppe, MD

University of Washington- Seattle Cancer Care Alliance

Recruiting

Seattle, Washington, United States, 98109

Contacts

Ralph Ermoian, MD

ralphpe@uw.edu

Principal Investigator:

Ralph Ermoian, MD

University Health Network - Princess Margaret Hospital

Recruiting

Toronto, Ontario, Canada, M5G 2C1

Contacts

Derek Tsang, MD

derek.tsang@uhn.ca

Principal Investigator:

Derek Tsang, MD

More Information

Sponsor

Massachusetts General Hospital

Last update posted

May 14, 2026

Last verified

May, 2026

Keywords

  • Proton Therapy
  • Pediatrics
  • Radiation Oncology
  • Photon Therapy

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Massachusetts General Hospital on 2026-05-14.