Recruiting

Observational StudyPilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy

Sponsor:

UCLA

Code:

NCT01771718

Conditions

Skin Lesion

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Interventions

Multiphoton microscopy-based tomograph.

Study Details

Brief summary:

The purpose of this pilot study is to employ multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin lesions for characterization of their morphologic and functional features.

Conditions

Skin Lesion

Study ID

NCT01771718

Start date

Apr, 2012

Status verified date

Aug, 2026

Completion date

Dec, 2028

Anticipated

Primary completion date

Dec, 2028

Anticipated

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Inclusion Criteria:

Male or Female all age groups
Ability to understand and carry out subject instructions

Exclusion Criteria:

Pregnant women

Study Design

Enrollment

250 participants

Anticipated

Interventions and Outcome Measures

Arms

Human skin

Multiphoton microscopy imaging to collect information about changes in skin cells and fibrilar structure.

Interventions

Multiphoton microscopy-based tomograph.

non-invasive optical biopsy

Primary outcome measure

high-resolution images of skin [ Time Frame: up to 12 months ]

Central Contacts and Locations

Central contacts

Hanna Kim

949-824-2251 hhkim3@uci.edu

Mihaela Balu, PhD

mbalu@uci.edu

Locations

Beckman Laser Institute Medical Clinic

Recruiting

Irvine, California, United States, 92612

Contacts

Hanna Kim

949-824-2251 hhkim3@uci.edu

Principal Investigator:

Kristen Kelly, MD

More Information

Sponsor

University of California, Irvine

Last update posted

Aug 31, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of California, Irvine on 2026-08-31.